Synthesis of pyrrolidinone derivatives from aniline, an aldehyde and diethyl acetylenedicarboxylate in an ethanolic citric acid solution under ultrasound irradiation

被引：123

作者：

Ahankar, Hamideh ^{[1
]}

Ramazani, Ali ^{[1
]}

Slepokura, Katarzyna ^{[2
]}

Lis, Tadeusz ^{[2
]}

Joo, Sang Woo ^{[3
]}

机构：

[1] Univ Zanjan, Dept Chem, POB 45195-313, Zanjan, Iran

[2] Univ Wroclaw, Fac Chem, 14 Joliot Curie St, PL-50383 Wroclaw, Poland

[3] Yeungnam Univ, Sch Mech Engn, Gyongsan 712749, South Korea

来源：

GREEN CHEMISTRY | 2016年 / 18卷 / 12期

基金：

新加坡国家研究基金会;

关键词：

ENVIRONMENTALLY FRIENDLY SYNTHESIS; ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; 4-COMPONENT SYNTHESIS; 3-COMPONENT REACTION; EFFICIENT SYNTHESIS; ORGANIC-SYNTHESIS; CATALYST; ORGANOCATALYST; NANOPARTICLES;

D O I：

10.1039/c6gc00157b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ultrasound-promoted one-pot multicomponent synthesis of substituted 3-pyrrolin-2-ones using citric acid as a green additive in a green solvent is reported. Citric acid catalyzed the reaction efficiently without the need for any other harmful organic reagents. Clean reaction profile, easy work-up procedure, excellent yields and short reaction times are some remarkable features of this method. The utilization of ultrasound irradiation makes this method potentially very useful, fast, clean and convenient.

引用

页码：3582 / 3593

页数：12

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