Synthesis of pyrrolidinone derivatives from aniline, an aldehyde and diethyl acetylenedicarboxylate in an ethanolic citric acid solution under ultrasound irradiation

被引：119
作者：
Ahankar, Hamideh [1 ]
Ramazani, Ali [1 ]
Slepokura, Katarzyna [2 ]
Lis, Tadeusz [2 ]
Joo, Sang Woo [3 ]
机构：
[1] Univ Zanjan, Dept Chem, POB 45195-313, Zanjan, Iran
[2] Univ Wroclaw, Fac Chem, 14 Joliot Curie St, PL-50383 Wroclaw, Poland
[3] Yeungnam Univ, Sch Mech Engn, Gyongsan 712749, South Korea
来源：
GREEN CHEMISTRY | 2016年 / 18卷 / 12期
基金：
新加坡国家研究基金会;
关键词：
ENVIRONMENTALLY FRIENDLY SYNTHESIS; ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; 4-COMPONENT SYNTHESIS; 3-COMPONENT REACTION; EFFICIENT SYNTHESIS; ORGANIC-SYNTHESIS; CATALYST; ORGANOCATALYST; NANOPARTICLES;
D O I：
10.1039/c6gc00157b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The ultrasound-promoted one-pot multicomponent synthesis of substituted 3-pyrrolin-2-ones using citric acid as a green additive in a green solvent is reported. Citric acid catalyzed the reaction efficiently without the need for any other harmful organic reagents. Clean reaction profile, easy work-up procedure, excellent yields and short reaction times are some remarkable features of this method. The utilization of ultrasound irradiation makes this method potentially very useful, fast, clean and convenient.
引用
收藏
页码：3582 / 3593
页数：12
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