A new biflavonoid from Solanum dulcamara L. and investigation of anti-hyperglycaemic activity of its fruit extract

被引：11
|
作者：
Sabudak, Temine [1 ]
Kaya, Oktay [2 ]
Cukurova, Elif [1 ]
机构：
[1] Namik Kemal Univ, Fac Sci & Letters, Dept Chem, TR-59860 Tekirdag, Turkey
[2] Trakya Univ, Dept Physiol, Fac Med, TR-22030 Edirne, Turkey
来源：
NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 04期
关键词：
Solonaceae; Solanum dulcamara; biflavonoid; anti-hyperglycaemic activity; GLYCOSIDES; STEROLS;
D O I：
10.1080/14786419.2014.928878
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new biflavone, 6,2 ',3 '',5 '',4"'-pentahydroxy-3,7 ''-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, beta-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effect of S. dulcamara was investigated using diabetic rats. The anti-hyperglycaemic activity of the fruit extract of S. dulcamara was presented for the first time in this study.
引用
收藏
页码：308 / 314
页数：7
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