Three newly identified HLA-B alleles: B*5124, B*5306, B*5307 and confirmation of B*0809 and B*5606

被引:6
作者
Anholts, JDH [1 ]
Kemps-Mols, B [1 ]
Verduijn, W [1 ]
Oudshoorn, M [1 ]
Schreuder, GMT [1 ]
机构
[1] Leiden Univ, Med Ctr, Dept Immunohematol & Blood Transfus, NL-2300 RC Leiden, Netherlands
来源
TISSUE ANTIGENS | 2001年 / 58卷 / 01期
关键词
HLA-B*5124; HLA-B*5306; HLA-B*5307; HLA-B*5606; HLA-B*0809; HLA serology; PCR-SBT;
D O I
10.1034/j.1399-0039.2001.580107.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Five HLA-B sequences are described which have been detected as irregular patterns during routine molecular typing. Sequencing of HLA-B exon 2 and 3, both heterozygous and after group specific amplification, revealed three new HLA-B alleles: B*5124, B*5306 and B*5307, whereas the sequences of B*0809 and B*5606 were confirmed, Serological typing showed that B*0809 is expressed as a regular B8, B*5124 as a regular B51, B*5306 as a B51/B53-like variant and B*5606 as a B'blank'-Bw6.
引用
收藏
页码:38 / 41
页数:4
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