"Mycobacterium tilburgii" Infection in Two Immunocompromised Children: Importance of Molecular Tools in Culture-Negative Mycobacterial Disease Diagnosis

被引：12

作者：

Hartwig, Nico G. ^{[1
]}

Warris, Adilia ^{[2
]}

van de Vosse, Esther ^{[3
]}

van der Zanden, Adri G. M. ^{[4
]}

Schulin-Casonato, Tanja ^{[5
]}

van Ingen, Jakko ^{[5
]}

van Hest, Rob ^{[6
]}

机构：

[1] Erasmus MC Sophia Childrens Hosp, Dept Pediat, Subdiv Pediat Infect Dis & Immunol, NL-3000 CB Rotterdam, Netherlands

[2] Radboud Univ Nijmegen, Med Ctr, Dept Pediat Infect Dis & Immunol, NL-6525 ED Nijmegen, Netherlands

[3] Leiden Univ, Med Ctr, Dept Infect Dis, Leiden, Netherlands

[4] Lab Med Microbiol & Publ Hlth, Enschede, Netherlands

[5] Radboud Univ Nijmegen, Med Ctr, Dept Clin Microbiol, NL-6525 ED Nijmegen, Netherlands

[6] Reg Publ Hlth Serv Rotterdam Rijnmond, Dept Infect Dis Control, TB Control Sect, Rotterdam, Netherlands

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 12期

关键词：

GROWING MYCOBACTERIA; DIFFERENTIATION; IDENTIFICATION; NETHERLANDS;

D O I：

10.1128/JCM.05460-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

"Mycobacterium tilburgii" is a nontuberculous mycobacterium that cannot be cultured by current techniques. It is described as causing disseminated disease in adults. We present the first cases of disseminated disease in 2 immunocompromised children. This paper stresses the importance of molecular techniques for correct mycobacterial identification and guidance to immunological diagnosis.

引用

页码：4409 / 4411

页数：3

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