New building blocks for the dendritic spine

被引:8
作者
Segal, M [1 ]
机构
[1] Weizmann Inst Sci, Dept Neurobiol, IL-76100 Rehovot, Israel
关键词
D O I
10.1016/S0896-6273(01)00368-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Two recent studies by Sheng and associates (Pak et al., 2001; Sala et al., 2001) provide an elegant molecular analysis of the role of a spine-specific protein, SPAR, and the synaptic proteins Shank and Homer, in regulating dendritic spine morphology, and the possible functional consequences of this regulation.
引用
收藏
页码:169 / 171
页数:3
相关论文
共 13 条
[1]  
El-Hussein AE, 2000, SCIENCE, V290, P1364
[2]   Functional plasticity triggers formation and pruning of dendritic spines in cultured hippocampal networks [J].
Goldin, M ;
Segal, M ;
Avignone, E .
JOURNAL OF NEUROSCIENCE, 2001, 21 (01) :186-193
[3]  
Hayashi K, 1999, J NEUROSCI, V19, P3918
[4]   Spike-associated fast contraction of dendritic spines in cultured hippocampal neurons [J].
Korkotian, E ;
Segal, M .
NEURON, 2001, 30 (03) :751-758
[5]   Actin-based plasticity in dendritic spines [J].
Matus, A .
SCIENCE, 2000, 290 (5492) :754-758
[6]   Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP [J].
Pak, DTS ;
Yang, SY ;
Rudolph-Correia, S ;
Kim, E ;
Sheng, M .
NEURON, 2001, 31 (02) :289-303
[7]   The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis [J].
Penzes, P ;
Johnson, RC ;
Sattler, R ;
Zhang, XQ ;
Huganir, RL ;
Kambampati, V ;
Mains, RE ;
Eipper, BA .
NEURON, 2001, 29 (01) :229-242
[8]   Regulation of dendritic spine morphology and synaptic function by Shank and Homer [J].
Sala, C ;
Piëch, V ;
Wilson, NR ;
Passafaro, M ;
Liu, GS ;
Sheng, M .
NEURON, 2001, 31 (01) :115-130
[9]   Dendritic spine formation and pruning: common cellular mechanisms? [J].
Segal, M ;
Korkotian, E ;
Murphy, DD .
TRENDS IN NEUROSCIENCES, 2000, 23 (02) :53-57
[10]  
Sorra KE, 2000, HIPPOCAMPUS, V10, P501, DOI 10.1002/1098-1063(2000)10:5<501::AID-HIPO1>3.3.CO