Synthesis of New 3-Substituted Indole Derivatives

被引：7

作者：

Hassaneen, Huwaida M. E. ^{[1
]}

Pagni, Richard M. ^{[2
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt

[2] Fac Tennessee, Dept Chem, Knoxville, TN USA

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2010年 / 65卷 / 12期

关键词：

3-Cyanoacetyl-2-methylindole; Thioacetanilide; Hydrazonoyl Halides; Thiadiazole; Thiazole; BISINDOLE ALKALOIDS; MARINE SPONGE; A-D; TOPSENTIN; FAMILY;

D O I：

10.1515/znb-2010-1213

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Treatment of 3-cyanoacetyl-2-methylindole (1) with phenyl isothiocyanate gave the corresponding thioacelanilicle derivative 3. The thioacetanilide 3 was utilized as the key intermediate for the synthesis of some new 1,3,4-thiadiazole (6a, b and 9a - e), thiophene (Ha, b), thiazolidin-4-one (4), thiazole (12 and 13), and benzothiazole (15) derivatives. The structures of the new compounds were elucidated on the basis of elemental analyses and spectral data.

引用

页码：1491 / 1497

页数：7

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