Nano optical and electrochemical sensors and biosensors for detection of narrow therapeutic index drugs

被引:6
作者
Shayesteh, Omid Heydari [1 ,2 ,3 ]
Mahjub, Reza [4 ]
Ranjbar, Akram [3 ,5 ]
Derakhshandeh, Katayoun [4 ]
Jamshidi, Mahdi [5 ]
机构
[1] Hamadan Univ Med Sci, Sch Pharm, Dept Med Chem, Hamadan, Hamadan, Iran
[2] Hamadan Univ Med Sci, Res Ctr Mol Med, Hamadan, Hamadan, Iran
[3] Hamadan Univ Med Sci, Nutr Hlth Res Ctr, Hamadan, Hamadan, Iran
[4] Hamadan Univ Med Sci, Sch Pharm, Dept Pharmaceut, Hamadan, Hamadan, Iran
[5] Hamadan Univ Med Sci, Sch Pharm, Dept Toxicol & Pharmacol, Hamadan, Hamadan, Iran
关键词
Nanotechnology; Biosensor; Narrow therapeutic index drugs; Nano optical and electrochemical sensor; GLASSY-CARBON ELECTRODE; PERFORMANCE LIQUID-CHROMATOGRAPHY; GLUCONIC ACID DETERMINATION; CDTE QUANTUM DOTS; INJECTION CHEMILUMINESCENCE DETERMINATION; WAVE VOLTAMMETRIC DETERMINATION; COATED MAGNETIC NANOPARTICLES; CAPPED SILVER NANOPARTICLES; NANOTUBES PASTE ELECTRODE; SCREEN-PRINTED ELECTRODE;
D O I
10.1007/s00604-021-05003-9
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
For the first time, a comprehensive review is presented on the quantitative determination of narrow therapeutic index drugs (NTIDs) by nano optical and electrochemical sensors and biosensors. NTIDs have a narrow index between their effective doses and those at which they produce adverse toxic effects. Therefore, accurate determination of these drugs is very important for clinicians to provide a clear judgment about drug therapy for patients. Routine analytical techniques have limitations such as being expensive, laborious, and time-consuming, and need a skilled user and therefore the nano/(bio)sensing technology leads to high interest.
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页数:42
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