Nano optical and electrochemical sensors and biosensors for detection of narrow therapeutic index drugs

被引：6

作者：

Shayesteh, Omid Heydari ^{[1
,2
,3
]}

Mahjub, Reza ^{[4
]}

Ranjbar, Akram ^{[3
,5
]}

Derakhshandeh, Katayoun ^{[4
]}

Jamshidi, Mahdi ^{[5
]}

机构：

[1] Hamadan Univ Med Sci, Sch Pharm, Dept Med Chem, Hamadan, Hamadan, Iran

[2] Hamadan Univ Med Sci, Res Ctr Mol Med, Hamadan, Hamadan, Iran

[3] Hamadan Univ Med Sci, Nutr Hlth Res Ctr, Hamadan, Hamadan, Iran

[4] Hamadan Univ Med Sci, Sch Pharm, Dept Pharmaceut, Hamadan, Hamadan, Iran

[5] Hamadan Univ Med Sci, Sch Pharm, Dept Toxicol & Pharmacol, Hamadan, Hamadan, Iran

来源：

MICROCHIMICA ACTA | 2021年 / 188卷 / 12期

关键词：

Nanotechnology; Biosensor; Narrow therapeutic index drugs; Nano optical and electrochemical sensor; GLASSY-CARBON ELECTRODE; PERFORMANCE LIQUID-CHROMATOGRAPHY; GLUCONIC ACID DETERMINATION; CDTE QUANTUM DOTS; INJECTION CHEMILUMINESCENCE DETERMINATION; WAVE VOLTAMMETRIC DETERMINATION; COATED MAGNETIC NANOPARTICLES; CAPPED SILVER NANOPARTICLES; NANOTUBES PASTE ELECTRODE; SCREEN-PRINTED ELECTRODE;

D O I：

10.1007/s00604-021-05003-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

For the first time, a comprehensive review is presented on the quantitative determination of narrow therapeutic index drugs (NTIDs) by nano optical and electrochemical sensors and biosensors. NTIDs have a narrow index between their effective doses and those at which they produce adverse toxic effects. Therefore, accurate determination of these drugs is very important for clinicians to provide a clear judgment about drug therapy for patients. Routine analytical techniques have limitations such as being expensive, laborious, and time-consuming, and need a skilled user and therefore the nano/(bio)sensing technology leads to high interest.

引用

页数：42

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