Pancreas Allograft Thrombosis

被引:49
作者
Muthusamy, Anand S. R. [2 ]
Giangrande, Paul L. F. [3 ,4 ]
Friend, Peter J. [1 ,2 ]
机构
[1] Univ Oxford, Churchill Hosp, Oxford Transplant Ctr, Nuffield Dept Surg, Oxford OX3 7LJ, England
[2] Churchill Hosp, Oxford Transplant Ctr, Oxford OX3 7LJ, England
[3] Churchill Hosp, Oxford Haemophilia Ctr, Oxford OX3 7LJ, England
[4] Churchill Hosp, Thrombosis Unit, Oxford OX3 7LJ, England
关键词
Pancreas transplantation; Complications; Thrombosis; Hypercoagulability; Diabetes mellitus; GRAFT THROMBOSIS; KIDNEY TRANSPLANTATION; COMPLICATIONS; OUTCOMES; OBESITY;
D O I
10.1097/TP.0b013e3181eb2ea0
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Thrombosis of the transplanted pancreas is a common and often catastrophic event. Predisposing factors include the hypercoagulable state of many patients with diabetic renal failure, preservation-related graft endothelial injury, and low-velocity venous flow. Clinical management includes optimization of modifiable risk factors, controlled anticoagulation, graft monitoring, and early therapeutic intervention.
引用
收藏
页码:705 / 707
页数:3
相关论文
共 20 条
  • [1] Pancreas graft thrombosis - Is there a role for trypsin
    Benz, S
    Busing, M
    Kruger, B
    Mayer, JM
    Obermaier, R
    Keck, T
    Pfeffer, F
    Hopt, UT
    [J]. PANCREAS, 2004, 28 (01) : 75 - 79
  • [2] Hypercoagulable state associated with kidney-pancreas transplantation. Thromboelastogram-directed anti-coagulation and implications for future therapy
    Burke, GW
    Ciancio, G
    Figueiro, J
    Buigas, R
    Olson, L
    Roth, D
    Kupin, W
    Miller, J
    [J]. CLINICAL TRANSPLANTATION, 2004, 18 (04) : 423 - 428
  • [3] Pancreatico-renal composite transplant: a new technique designed to decrease pancreatic graft thrombosis
    Dafoe, DC
    Ratner, LE
    [J]. CLINICAL TRANSPLANTATION, 2005, 19 (05) : 690 - 693
  • [4] Pancreas transplantation: The histologic morphology of graft loss and clinical correlations
    Drachenberg, CB
    Papadimitriou, JC
    Farney, A
    Wiland, A
    Blahut, S
    Fink, JC
    Philosophe, B
    Schweitzer, E
    Lal, T
    Anderson, L
    Bartlett, ST
    [J]. TRANSPLANTATION, 2001, 71 (12) : 1784 - 1791
  • [5] Single-shot antithrombin in human pancreas-kidney transplantation: reduction of reperfusion pancreatitis and prevention of graft thrombosis
    Fertmann, Jan M.
    Wimmer, Cosmas D.
    Arbogast, Helmut P.
    Illner, Wolf-Dieter
    Tarabichi, Anwar
    Calasan, Ivan
    Dieterle, Christian
    Land, Walter
    Jauch, Karl-Walther
    Johannes, N. Hoffmann
    [J]. TRANSPLANT INTERNATIONAL, 2006, 19 (06) : 458 - 465
  • [6] FRIDELL JA, 2010, CLIN TRANSPLANT
  • [7] Obesity predicts increased overall complications following pancreas transplantation
    Hanish, SI
    Petersen, RP
    Collins, BH
    Tuttle-Newhall, J
    Marroquin, CE
    Kuo, PC
    Butterly, DW
    Smith, SR
    Desai, DM
    [J]. TRANSPLANTATION PROCEEDINGS, 2005, 37 (08) : 3564 - 3566
  • [8] Technical failures after pancreas transplants: Why grafts fail and the risk factors - A multivariate analysis
    Humar, A
    Ramcharan, T
    Kandaswamy, R
    Gruessner, RWG
    Gruessner, AC
    Sutherland, DER
    [J]. TRANSPLANTATION, 2004, 78 (08) : 1188 - 1192
  • [9] The impact of donor obesity on outcomes after cadaver pancreas transplants
    Humar, A
    Ramcharan, T
    Kandaswamy, R
    Gruessner, RWG
    Gruessner, AG
    Sutherland, DER
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2004, 4 (04) : 605 - 610
  • [10] Incidence of pancreas graft thrombosis in portoiliac and portocaval venous anastomosis
    Jiménez, C
    Manrique, A
    Herrero, ML
    Meneu, JC
    Abradelo, M
    Gutierrez, E
    Morales, JM
    Ortuño, T
    Praga, M
    Andrés, A
    Morales, E
    Moreno, E
    [J]. TRANSPLANTATION PROCEEDINGS, 2005, 37 (09) : 3977 - 3978