Enantioselective reduction of ortho-substituted acetophenones by bacterial strains isolated from medium enriched with biphenyl or diesel fuel

被引：22

作者：

Andrade, LH

Comasseto, JV

Rodrigues, DF

Pellizari, VH

Porto, ALM

机构：

[1] Univ Sao Paulo, Inst Quim, Lab Quim Fina & Biocatalise, BR-05508900 Sao Paulo, SP, Brazil

[2] Univ Sao Paulo, Inst Ciencias Biomed, Lab Microbiol Ambiental, BR-05508900 Sao Paulo, SP, Brazil

[3] Univ Sao Paulo, Inst Quim, Lab Quim Fina & Biocatalise, BR-05508900 Sao Paulo, SP, Brazil

来源：

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 2005年 / 33卷 / 3-6期

基金：

巴西圣保罗研究基金会;

关键词：

bioreduction; bacteria; ketone; tellurium; alcohol; selenium;

D O I：

10.1016/j.molcatb.2005.02.003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Application of 21 new bacterial strains from natural environments (coastal plain of Santos and Atlantic Rain Forest, Sao Paulo, Brazil) in the asymmetric reduction of acetophenone derivatives is described. The bioreduction was carried out with whole bacterial cells leading to (S)-chiral alcohols in up to >= 99% e.e. The (S)-(-)- I -(2-bromo-phenyl)-ethanol was employed in the preparation of chiral tellurium derivatives. (c) 2005 Elsevier B.V. All rights reserved.

引用

收藏

页码：73 / 79

页数：7

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