Hydroxyapatite's solubility may cause loosening of coated implants

被引：9

作者：

Berger, G

Ploska, U

Willmann, G

机构：

[1] BAM Berlin, Fed Inst Mat Res & Testing, DE-12200 Berlin, Germany

[2] CeramTec AG, DE-73207 Plochingen, Germany

来源：

BIOCERAMICS | 2000年 / 192-1卷

关键词：

coated implants; hydroxyapatite HA; pH value; solubility;

D O I：

10.4028/www.scientific.net/KEM.192-195.111

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The aim of this investigation was to get some information how a late infection or a wound healing inflammation could act on calcium phosphate coated implants. For this purpose hydroxyapatite (commercial BIOLOX (R) osprovit) and calcium zirconium phosphate [CaZr4(PO4)(6)] were analyzed with regard to their solubility using two buffer solutions (TRIS-HCl and citric acid phosphate McIlvain) each of them with different pH values of 6.0 and 7.4, respectively. The results led to the conclusion that hydroxyapatite is less stable in a body environment when the local pH value decreases below 7.4. The consequence is that the hydroxyapatite coating. may be weakened if there is a late infection or wound healing inflammation. This may cause loosening of coated implants. Calcium zirconium phosphate could be an alternative coating material taking account of the absolute solubility values.

引用

页码：111 / 114

页数：4