N-chloro and N-bromosaccharins:: Valuable reagents for halogenation of electron rich aromatics and cohalogenation of alkenes

被引：37

作者：

de Souza, SPL ^{[1
]}

da Silva, JFM ^{[1
]}

de Mattos, MCS ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro, Inst Quim, BR-21945970 Rio De Janeiro, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2003年 / 14卷 / 05期

关键词：

cohalogenation; aromatic halogenation; N-halosaccharin;

D O I：

10.1590/S0103-50532003000500021

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Chloro- and N-bromosaccharins react with electron rich aromatic compounds (anisole, acetanilide, N,N-dimethylaniline) producing halogenated compounds. The reaction with N-bromosaccharin gives para-substituted compounds only, whereas N-chlorosaccharin produces orto and para mixtures (para isomer predominantly, ca. 4-5:1). The reactions of the N-halosaccharins with alkenes (cyclohexene, styrene, alpha-methylstyrene, and 1-hexene) give the corresponding halohydrins.

引用

页码：832 / 835

页数：4

共 16 条

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