Solvent-free synthesis of 1,4-disubstituted 1,2,3-triazoles using a low amount of Cu(PPh3)2NO3 complex

被引:136
|
作者
Wang, Dong [1 ,2 ]
Li, Na [1 ,2 ]
Zhao, Mingming [1 ,2 ]
Shi, Weilin [1 ,2 ]
Ma, Chaowei [1 ,2 ]
Chen, Baohua [1 ,2 ]
机构
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China
基金
美国国家科学基金会;
关键词
SITU CLICK CHEMISTRY; 1,3-DIPOLAR CYCLOADDITION; AZIDES; CATALYST; ALKYNES; NANOPARTICLES; INHIBITORS; EFFICIENCY; LIGATION;
D O I
10.1039/c0gc00381f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We have developed an environmentally friendly and highly efficient method for copper-catalyzed cycloaddition of organic azides and terminal alkynes under solvent-free conditions. The protocol uses the cheap and easy-to-prepare Cu(PPh3)(2)NO3 complex as the catalyst.
引用
收藏
页码:2120 / 2123
页数:4
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