Associative chemosensing by fluorescent macrocycle-dye complexes - a versatile enzyme assay platform beyond indicator displacement

被引：52
作者：
Biedermann, Frank [1 ]
Hathazi, Denisa [1 ]
Nau, Werner M. [1 ]
机构：
[1] Jacobs Univ Bremen, Dept Life Sci & Chem, D-28759 Bremen, Germany
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 24期
关键词：
HORSERADISH-PEROXIDASE; BETA-GALACTOSIDASE; INHIBITION; CALIXARENE; SYSTEMS;
D O I：
10.1039/c4cc10227d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A label-free in situ method to monitor reactions in real time by using fluorescent supramolecular chemosensors based on cucurbit[8]uril is presented. It allows sensing of enzymatic activity, inhibitor and activator screening, and analyte detection with unprecedented versatility and high sensitivity.
引用
收藏
页码：4977 / 4980
页数：4
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