Oral liposarcoma in elderly Case report and literature analysis

Rationale: Oral liposarcoma is an extremely rare lesion that is often clinically misdiagnosed as a benign lesion because of its asymptomatic and indolent clinical course. we report a case of atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) of buccal mucosa, provisionally diagnosed as lipoma. Patient concerns A 97-year-old female was referred to dentistry and oral surgery department with an asymptomatic mass on the right buccal mucosa which had been present for an unknown period of time. Diagnosis Magnetic resonance imaging demonstrated a well-circumscribed lesion at the right buccal mucosa, and a lipoma was suspected. Interventions Surgical removal was performed, and a diagnosis of ALT/WDL was made. She and her family refused additional treatment due to her age. Outcomes At the 10 months follow-up, the patient remained free of disease. Lessons The indolent clinical course and small size of oral liposarcoma can lead to provisional clinical diagnosis of benign lesion.