The role of PET/CT in cogan's syndrome

被引：19
作者：
Balink, H.
Bruyn, G. A. W.
机构：
[1] Med Ctr Leeuwarden, Dept Nucl Med, NL-8901 BR Leewarden, Netherlands
[2] Med Ctr Leeuwarden, Dept Rheumatol, NL-8901 BR Leeuwarden, Netherlands
来源：
CLINICAL RHEUMATOLOGY | 2007年 / 26卷 / 12期
关键词：
Cogan's syndrome; F18-FDG PET/CT; hearing loss; large-vessel vasculitis;
D O I：
10.1007/s10067-007-0663-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report on the case of a 60-year-old woman with complaints of fatigue, coughing, anorexia, atypical chest pain, recurrent fever, and also ear pain and hearing loss. A test for anti-neutrophil cytoplasmic antibody (ANCA) was myeloperoxidase positive with p-ANCA specificity. Laboratory acute phase parameters were increased. A 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography/computed tomography investigation showed pathological uptake in the aorta ascendens, with no other involvement of the large vessels. After therapy with methylprednisolon intravenously and later prednisolon orally with methothrexate, her general condition and hearing loss improved both subjectively and objectively. "Atypical" Cogan's syndrome was diagnosed on the basis of sensorineural deafness with improvement on steroids and large-vessel vasculitis of the aortic arch.
引用
收藏
页码：2177 / 2179
页数：3
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