Palladium-catalyzed Asymmetric Allylic Alkylation Using C2-symmetric Chiral Bidentate Bis(N-heterocyclic carbene) Ligands with the o-Xylylene Framework

被引：2

作者：

Yamaguchi, Yoshitaka ^{[1
]}

Suzuki, Yasutomo ^{[1
]}

Matsumoto, Sawako ^{[1
]}

Anezaki, Satoshi ^{[1
]}

Asami, Masatoshi ^{[1
]}

机构：

[1] Yokohama Natl Univ, Grad Sch Engn, Dept Adv Mat Chem, Hodogaya Ku, 79-5 Tokiwadai, Yokohama, Kanagawa 2408501, Japan

来源：

CHEMISTRY LETTERS | 2016年 / 45卷 / 07期

关键词：

N-Heterocyclic carbene; Palladium complex; Asymmetric allylic alkylation; N-HETEROCYCLIC CARBENES; STEREODIRECTING LIGANDS; COMPLEXES; AMINATION; PD; ALLYLATION; MECHANISM; KINETICS;

D O I：

10.1246/cl.160235

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An asymmetric allylic alkylation reaction of 1,3-diphenyl-prop-2-en-1-y1 acetate with dimethyl malonate was examined using C-2-symmetric chiral bidentate bis(N-heterocyclic carbene)-based palladium catalysts. The alkylated product was obtained in 96% yield with good enantioselectivity (80% ee).

引用

页码：798 / 800

页数：3

共 46 条

[11] Phosphine-phosphite ligands in the palladium-catalyzed asymmetric allylic alkylation: Electronic and steric effects [J].