Nanoengineered polymer capsules:: Tools for detection, controlled delivery, and site-specific manipulation

被引：237
|
作者：
Sukhorukov, GB [1 ]
Rogach, AL
Zebli, B
Liedl, T
Skirtach, AG
Köhler, K
Antipov, AA
Gaponik, N
Susha, AS
Winterhalter, M
Parak, WJ
机构：
[1] Max Planck Inst Colloids & Interface, D-14424 Potsdam, Germany
[2] Univ Munich, Photon & Optoelect Grp, Dept Phys, D-80799 Munich, Germany
[3] Univ Munich, Ctr Nanosci CeNS, D-80799 Munich, Germany
[4] Univ Hamburg, Inst Chem Phys, D-20146 Hamburg, Germany
[5] Int Jacobs Univ Bremen, Sch Sci & Engn, D-28759 Bremen, Germany
[6] Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
来源：
SMALL | 2005年 / 1卷 / 02期
关键词：
biomaterials; drug delivery; microcapsules; polyelectrolytes; quantum dots;
D O I：
10.1002/smll.200400075
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The aim of nanobiotechnology is the discovery of new drug and their delivery systems, including building up of multifunctional capsules as intelligent drug carriers: once injected somewhere into blood stream the capsules would find their target, is discussed. The combination of physical, chemical, and biological approaches for designing the capsule properties is necessary to develop the capsule technology towards biological applications. It is suggested that the development of multifunctional carrier system will design surfaces and interior composition as delivery systems with (remote) stimuli-controlled release will have a strong impact on biotechnology. With multifunctionasl capsules, direction and control of the uptake of drugs by pathological cells with different methods is possible.
引用
收藏
页码：194 / 200
页数：7
相关论文
共 50 条
  • [41] Magnetic Mesoporous Silica Gated with Doped Carbon Dot for Site-Specific Drug Delivery, Fluorescence, and MR Imaging
    Das, Rahul K.
    Pramanik, Arindam
    Majhi, Megharay
    Mohapatra, Sasmita
    LANGMUIR, 2018, 34 (18) : 5253 - 5262
  • [42] Light-stimulated cargo release from a core-shell structured nanocomposite for site-specific delivery
    Cai, Yun
    Ling, Li
    Li, Xiaofang
    Chen, Meng
    Su, Likai
    JOURNAL OF SOLID STATE CHEMISTRY, 2015, 226 : 179 - 185
  • [43] Site-Specific Protection and Dual Labeling of Human Epidermal Growth Factor (hEGF) for Targeting, Imaging, and Cargo Delivery
    Sonntag, Michael H.
    Ibach, Jenny
    Nieto, Lidia
    Verveer, Peter J.
    Brunsveld, Luc
    CHEMISTRY-A EUROPEAN JOURNAL, 2014, 20 (20) : 6019 - 6026
  • [44] Ultrasmall TPGS-PLGA Hybrid Nanoparticles for Site-Specific Delivery of Antibiotics into Pseudomonas aeruginosa Biofilms in Lungs
    Wan, Feng
    Bohr, Soren S. -R
    Klodzinska, Sylvia Natalie
    Jumaa, Haidar
    Huang, Zheng
    Nylander, Tommy
    Thygesen, Mikkel Boas
    Sorensen, Kasper Kildegaard
    Jensen, Knud Jorgen
    Sternberg, Claus
    Hatzakis, Nikos
    Nielsen, Hanne Morck
    ACS APPLIED MATERIALS & INTERFACES, 2020, 12 (01) : 380 - 389
  • [45] Naringenin-Functionalized Multi-Walled Carbon Nanotubes: A Potential Approach for Site-Specific Remote-Controlled Anticancer Delivery for the Treatment of Lung Cancer Cells
    Morais, Renata P.
    Novais, Gabrielle B.
    Sangenito, Leandro S.
    Santos, Andre L. S.
    Priefer, Ronny
    Morsink, Margreet
    Mendonca, Marcelo C.
    Souto, Eliana B.
    Severino, Patricia
    Cardoso, Juliana C.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (12) : 1 - 14
  • [46] Hyaluronic acid-engineered Bcl-2 inhibitor nanocrystals for site-specific delivery to breast tumor cells
    Panwar, Dilip
    Thakor, Pradip
    Sharma, Madhu
    Bakshi, Avijit Kumar
    Bhavana, Valamla
    Srivastava, Vaibhavi
    Mishra, Prabhat Ranjan
    Singh, Shashi Bala
    Mehra, Neelesh Kumar
    NANOMEDICINE, 2023, 18 (15) : 1005 - 1023
  • [47] Recent progress in nanomedicine-based combination cancer therapy using a site-specific co-delivery strategy
    Shen, Shiyang
    Liu, Meng
    Li, Teng
    Lin, Shiqi
    Mo, Ran
    BIOMATERIALS SCIENCE, 2017, 5 (08) : 1367 - 1381
  • [48] Targeting of Magnetic Nanoparticle-coated Microbubbles to the Vascular Wall Empowers Site-specific Lentiviral Gene Delivery in vivo
    Heun, Yvonn
    Hildebrand, Staffan
    Heidsieck, Alexandra
    Gleich, Bernhard
    Anton, Martina
    Pircher, Joachim
    Ribeiro, Andrea
    Mykhaylyk, Olga
    Eberbeck, Dietmar
    Wenzel, Daniela
    Pfeifer, Alexander
    Woernle, Markus
    Kroetz, Florian
    Pohl, Ulrich
    Mannell, Hanna
    THERANOSTICS, 2017, 7 (02): : 295 - 307
  • [49] CROSSLINKED BIODEGRADABLE ALGINATE HYDROGEL FLOATING BEADS FOR STOMACH SITE SPECIFIC CONTROLLED DELIVERY OF METRONIDAZOLE
    Giri, Tapan Kumar
    Verma, Saurabh
    Alexander, Amit
    Ajazuddin
    Badwaik, Hemant
    Tripathy, Minaketan
    Tripathi, Dulal Krishna
    FARMACIA, 2013, 61 (03) : 533 - 550
  • [50] Site-Specific Drug Delivery Using Injectable pH-Responsive Biopolymeric Hydrogel: Instant Crosslinking and Shear Thinning
    Ghosh, Sanjib
    Manna, Kalipada
    Chakraborty, Kanta
    Dhara, Santanu
    Pal, Sagar
    ACS APPLIED POLYMER MATERIALS, 2025, 7 (07): : 4166 - 4176
12345