FKBP5 Regulates HPA Axis Activity by Fine Tuning the Mineralocorticoid/Glucocorticoid Receptor Balance in the Hippocampus

被引:0
|
作者
Hartmann, Jakob [1 ]
Klengel, Claudia [1 ]
McCullough, Kenneth [1 ]
Klengel, Torsten [1 ]
Joels, Marian [1 ]
Dudek, Serena [1 ]
Sarabdjitsingh, Angela [1 ]
Schmidt, Mathias V. [1 ]
Ressler, Kerry [1 ]
机构
[1] Harvard Univ, McLean Hosp, Sch Med, Belmont, MA USA
关键词
HPA Axis; Glucocorticoid Receptor; Mineralocorticoid Receptor; FKBP5; Hippocampus;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
M79
引用
收藏
页码:118 / 119
页数:2
相关论文
共 25 条
  • [1] FKBP5 Regulates HPA Axis Activity by Fine-Tuning the Mineralocorticoid:Glucocorticoid Receptor Balance in the Hippocampus
    Hartmann, Jakob
    Bajaj, Thomas
    Klengel, Claudia
    Chatzinakos, Christos
    Dedic, Nina
    McCullough, Kenneth
    Lardenoije, Roy
    Joels, Marian
    Meijer, Onno
    McCann, Katharine
    Dudek, Serena
    Sarabdjitsingh, Angela
    Daskalakis, Nikolaos
    Klengel, Torsten
    Gassen, Nils
    Schmidt, Mathias V.
    Ressler, Kerry
    NEUROPSYCHOPHARMACOLOGY, 2020, 45 (SUPPL 1) : 317 - 317
  • [2] Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour
    Harris, A. P.
    Holmes, M. C.
    de Kloet, E. R.
    Chapman, K. E.
    Seckl, J. R.
    PSYCHONEUROENDOCRINOLOGY, 2013, 38 (05) : 648 - 658
  • [3] Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5
    Hartmann, Jakob
    Bajaj, Thomas
    Klengel, Claudia
    Chatzinakos, Chris
    Ebert, Tim
    Dedic, Nina
    McCullough, Kenneth M.
    Lardenoije, Roy
    Joels, Marian
    Meijer, Onno C.
    McCann, Katharine E.
    Dudek, Serena M.
    Sarabdjitsingh, R. Angela
    Daskalakis, Nikolaos P.
    Klengel, Torsten
    Gassen, Nils C.
    Schmidt, Mathias, V
    Ressler, Kerry J.
    CELL REPORTS, 2021, 35 (09):
  • [4] The Effect of Nicotine on HPA Axis Activity in Females is Modulated by the FKBP5 Genotype
    Koopmann, Anne
    Bez, Jennifer
    Lemenager, Tagrid
    Hermann, Derik
    Dinter, Christina
    Reinhard, Iris
    Schuster, Rilana
    Wiedemann, Klaus
    Winterer, Georg
    Kiefer, Falk
    ANNALS OF HUMAN GENETICS, 2016, 80 (03) : 154 - 161
  • [5] Interaction Between Glucocorticoid Receptors and FKBP5 in Regulating Neurotransmission of the Hippocampus
    Zhang, Seungjae
    Cheon, Myunghyun
    Park, Hoyong
    Kim, Taejoon
    Chung, ChiHye
    NEUROSCIENCE, 2022, 483 : 95 - 103
  • [6] The role of childhood trauma, HPA axis reactivity and FKBP5 genotype on cognition in healthy individuals
    Ferrer, Alex
    Soria, Virginia
    Salvat-Pujol, Neus
    Martorell, Lourdes
    Armario, Antonio
    Urretavizcaya, Mikel
    Gutierrez-Zotes, Alfonso
    Monreal, Jose Antonio
    Crespo, Jose Manuel
    Massaneda, Clara
    Vilella, Elisabet
    Palao, Diego
    Menchon, Jose Manuel
    Labad, Javier
    PSYCHONEUROENDOCRINOLOGY, 2021, 128
  • [7] Gene and protein alterations of FKBP5 and glucocorticoid receptor in the amygdala of suicide victims
    Perez-Ortiz, Jose M.
    Garcia-Gutierrez, Maria S.
    Navarrete, Francisco
    Giner, Salvador
    Manzanares, Jorge
    PSYCHONEUROENDOCRINOLOGY, 2013, 38 (08) : 1251 - 1258
  • [8] Glucocorticoid-Responsive Transcription Factor Kruppel-Like Factor 9 Regulates fkbp5 and Metabolism
    Gans, Ian M.
    Grendler, Janelle
    Babich, Remy
    Jayasundara, Nishad
    Coffman, James A.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
  • [9] Accumulation of Cytoplasmic Glucocorticoid Receptor Is Related to Elevation of FKBP5 in Lymphocytes of Depressed Patients
    Iva Lukic
    Milos Mitic
    Ivan Soldatovic
    Milica Jovicic
    Nadja Maric
    Jelena Radulovic
    Miroslav Adzic
    Journal of Molecular Neuroscience, 2015, 55 : 951 - 958
  • [10] Accumulation of Cytoplasmic Glucocorticoid Receptor Is Related to Elevation of FKBP5 in Lymphocytes of Depressed Patients
    Lukic, Iva
    Mitic, Milos
    Soldatovic, Ivan
    Jovicic, Milica
    Maric, Nadja
    Radulovic, Jelena
    Adzic, Miroslav
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2015, 55 (04) : 951 - 958