MicroRNAs are potential prognostic and therapeutic targets in diabetic osteoarthritis

被引：22
|
作者：
Shi Jingsheng [1 ]
Wei Yibing [1 ]
Xia Jun [1 ]
Wang Siqun [1 ]
Wu Jianguo [1 ]
Chen Feiyan [1 ]
Huang Gangyong [1 ]
Chen Jie [1 ]
机构：
[1] Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China
来源：
JOURNAL OF BONE AND MINERAL METABOLISM | 2015年 / 33卷 / 01期
关键词：
MicroRNA; Type II diabetes; Osteoarthritis chondrocyte; GLYCATION END-PRODUCTS; MESENCHYMAL PROGENITOR CELLS; ARTICULAR-CARTILAGE; STEM-CELLS; CHONDROGENIC DIFFERENTIATION; CHONDROCYTE PROLIFERATION; ELEVATED MICRORNA-34A; KNEE OSTEOARTHRITIS; MEDIATED REGULATION; EXPRESSION;
D O I：
10.1007/s00774-014-0628-0
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Osteoarthritis is an aging-related degenerative disease that severely influences the elders' life quality. However, there have been few clinical approaches available until now. Currently, more knowledge of the pathology of osteoarthritis has been illustrated. Especially, diabetes can be the only predictor of osteoarthritis. Due to its outstanding characteristics, MicroRNA has been considered as an efficient target in treating diseases. In this review, we will discuss a new insight focusing on the roles of microRNA in the progression of osteoarthritis-induced by diabetes, especially type II diabetes mellitus.
引用
收藏
页码：1 / 8
页数：8
相关论文
共 50 条
  • [21] MicroRNAs and Lung Cancer: New Oncogenes and Tumor Suppressors, New Prognostic Factors and Potential Therapeutic Targets
    Ortholan, Cecile
    Puissegur, Marie-Pierre
    Ilie, Marius
    Barbry, Pascal
    Mari, Bernard
    Hofman, Paul
    CURRENT MEDICINAL CHEMISTRY, 2009, 16 (09) : 1047 - 1061
  • [22] Strategies to use microRNAs as therapeutic targets
    Krutzfeldt, Jan
    BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2016, 30 (05) : 551 - 561
  • [23] MicroRNAs serving as potential biomarkers and therapeutic targets in nasopharyngeal carcinoma: A critical review
    Lee, Katherine Ting-Wei
    Tan, Juan-King
    Lam, Alfred King-yin
    Gan, Sook-Yee
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2016, 103 : 1 - 9
  • [24] An update on microRNAs as potential novel therapeutic targets in testicular germ cell tumors
    De Martino, Marco
    Esposito, Francesco
    Chieffi, Paolo
    INTRACTABLE & RARE DISEASES RESEARCH, 2020, 9 (03) : 184 - 186
  • [25] Non-Canonical Targets of MicroRNAs: Role in Transcriptional Regulation, Disease Pathogenesis and Potential for Therapeutic Targets
    Ray, Aishwarya
    Sarkar, Abhisek
    Banerjee, Sounak
    Biswas, Kaushik
    MICRORNA, 2024, 13 (02) : 83 - 95
  • [26] Exosomal microRNAs: potential nanotherapeutic targets for diabetic kidney disease
    Han, Lulu
    Cai, Xiaoning
    Zhou, Hong
    NANOMEDICINE, 2023, 18 (23) : 1669 - 1680
  • [27] MicroRNAs: a novel class of potential therapeutic targets for cardiovascular diseases
    Zhen-wei Pan
    Yan-jie Lu
    Bao-feng Yang
    Acta Pharmacologica Sinica, 2010, 31 : 1 - 9
  • [28] MicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer
    Jafri, Mohammad Alam
    Zaidi, Syed Kashif
    Ansari, Shakeel Ahmed
    Al-Qahtani, Mohammed Hussein
    Shay, Jerry W.
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2015, 19 (12) : 1705 - 1723
  • [29] MicroRNAs in infectious diseases: potential diagnostic biomarkers and therapeutic targets
    Kimura, Muneyoshi
    Kothari, Sagar
    Gohir, Wajiha
    Camargo, Jose F.
    Husain, Shahid
    CLINICAL MICROBIOLOGY REVIEWS, 2023, 36 (04)
  • [30] MicroRNAs as Mediators of Adipose Thermogenesis and Potential Therapeutic Targets for Obesity
    Ma, Lunkun
    Gilani, Ankit
    Yi, Qian
    Tang, Liling
    BIOLOGY-BASEL, 2022, 11 (11):
12345