DNA vaccines for veterinary medicine.

被引:0
作者
Gerdts, V
Mettenleiter, TC
机构
[1] Bundesforschungsanstalt Viruskrankeiten Tiere, Friedrich Loeffler Inst, Inst Mol Biol, D-17498 Insel Riems, Germany
[2] Univ Saskatchewan, Vet Infect Dis Org, Saskatoon, SK S7N 0W0, Canada
来源
DEUTSCHE TIERARZTLICHE WOCHENSCHRIFT | 2001年 / 108卷 / 01期
关键词
review; DNA vaccines; immunology;
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
DNA vaccination represents one of the most recent novel approaches to vaccine development. Experimentally, DNA vaccines induce a broad range of long lasting immune responses including humoral and cell-mediated immunity against infectious diseases in humans and animals. Furthermore, DNA vaccines are potentially useful for the treatment of autoimmune diseases or cancer. However, most information on the efficacy of DNA vaccines has been generated in mice and studies in larger animals are limited. In this review, the potential application of DNA vaccines in livestock and pet animals are discussed. The principle of this new technology, its potency and future perspectives for use in veterinary medicine will be outlined.
引用
收藏
页码:3 / 10
页数:8
相关论文
共 98 条
  • [1] Aggarwal N, 1999, CAN J VET RES, V63, P148
  • [2] AKAGUCHI M, 1996, VACCINE, V14, P747
  • [3] DNA vaccination: Transfection and activation of dendritic cells as key events for immunity
    Akbari, O
    Panjwani, N
    Garcia, S
    Tascon, R
    Lowrie, D
    Stockinger, B
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (01) : 169 - 177
  • [4] Anderson ED, 1996, MOL MAR BIOL BIOTECH, V5, P114
  • [5] Protection of pigs against classical swine fever with DNA-delivered gp55
    Andrew, ME
    Morrissy, CJ
    Lenghaus, C
    Oke, PG
    Sproat, KW
    Hodgson, ALM
    Johnson, MA
    Coupar, BEH
    [J]. VACCINE, 2000, 18 (18) : 1932 - 1938
  • [6] Immunization with a DNA plasmid encoding the SAG1 (P30) protein of Toxoplasma gondii is immunogenic and protective in rodents
    Angus, CW
    Klivington-Evans, D
    Dubey, JP
    Kovacs, JA
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2000, 181 (01) : 317 - 324
  • [7] Nucleic acid vaccination against Toxoplasma gondii in mice
    Angus, CW
    Klivington, D
    Wyman, J
    Kovacs, JA
    [J]. JOURNAL OF EUKARYOTIC MICROBIOLOGY, 1996, 43 (05) : S117 - S117
  • [8] Babiuk LA, 1998, CURR TOP MICROBIOL, V226, P90
  • [9] Mucosal immunization with DNA encoding influenza hemagglutinin
    Ban, EM
    vanGinkel, FW
    Simecka, JW
    Kiyono, H
    Robinson, HL
    McGhee, JR
    [J]. VACCINE, 1997, 15 (08) : 811 - 813
  • [10] Out on the farm with DNA vaccines
    Beard, CW
    Mason, PW
    [J]. NATURE BIOTECHNOLOGY, 1998, 16 (13) : 1325 - 1328