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One-Pot Synthesis Bodipy Nano-Precipitations for Prostate Cancer Treatment
被引:0
作者:
Wang, Jianan
[1
]
Tian, Chao
[1
]
Cao, Zhengguo
[1
]
机构:
[1] Yuebei Peoples Hosp, Dept Urol, Shaoguan 512000, Guangdong, Peoples R China
关键词:
One-Pot;
Bodipy;
Photodynamic Therapy;
Prostate Cancer;
TUMOR-TARGETED DELIVERY;
OSTEOBLAST PROMOTION;
CALCIUM SUPPLEMENT;
NANOPARTICLES;
THERAPY;
ROS;
ICG;
D O I:
10.1166/jbt.2022.3070
中图分类号:
Q813 [细胞工程];
学科分类号:
摘要:
Here in this study, we proposed a polystyrene maleic anhydride (PSMA) stabilized Bodipy nanoparticles (PB NPs) in a one-pot approach for the photodynamic therapy (PDT) of prostate cancer. The nanoparticle formed by precipitation method was then employed to treat PC-3 cells and PC-3 tumor bearing nude mice model. It was shown that this platform showed promising anticancer performance than free bodipy with reduced side effects.
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页码:1537 / 1541
页数:5
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