Optically active 1-(benzofuran-2-yl)ethanols and ethane-1,2-diols by enantiotopic selective bioreductions

被引：55
|
作者：
Paizs, C
Tosa, M
Majdik, C
Moldovan, P
Novák, L
Kolonits, P
Marcovici, A
Irimie, FD
Poppe, L
机构：
[1] Univ Babes Bolyai, Dept Biochem & Biochem Engn, RO-3400 Cluj Napoca, Romania
[2] Budapest Univ Technol & Econ, Hungarian Acad Sci, Inst Organ Chem, H-1111 Budapest, Hungary
[3] Budapest Univ Technol & Econ, Hungarian Acad Sci, Res Grp Alkaloid Chem, H-1111 Budapest, Hungary
[4] Terapia SA, Dept Bioequivalence Clin Trials, RO-3400 Cluj Napoca, Romania
来源：
TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 11期
关键词：
D O I：
10.1016/S0957-4166(03)00222-2
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Enantiotopic selective reduction of 1-(benzofuran-2-yl)ethanones 1a-d, 1-(benzofuran-2-yl)-2-hydroxyethanones 4a-c and 2-acetoxy-1-(benzofuran-2-yl)ethanones 3a-c was performed by baker's yeast for preparation of optically active (benzofuran-2-yl)carbinols [(S)-5a-d, (S)-6a-c and (R)-6a-c, enantiomeric excess from 55 to 93% ee]. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1495 / 1501
页数：7
相关论文
共 50 条
12345