Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis

被引：1

作者：

Oiwa, Hiroshi ^{[1
]}

Taniguchi, Kohei ^{[2
,3
]}

Miyoshi, Natsuki ^{[4
]}

Sasaki, Keiko ^{[5
]}

Ichimura, Kouichi ^{[2
]}

Kubota, Tetsushi ^{[6
]}

Sato, Daisuke ^{[6
]}

机构：

[1] Hiroshima City Hiroshima Citizens Hosp, Dept Rheumatol, Hiroshima, Japan

[2] Hiroshima City Hiroshima Citizens Hosp, Dept Pathol, Hiroshima, Japan

[3] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol, Okayama, Japan

[4] Hiroshima City Hiroshima Citizens Hosp, Dept Clin Lab, Hiroshima, Japan

[5] Hiroshima City Hiroshima Citizens Hosp, Dept Dermatol, Hiroshima, Japan

[6] Hiroshima City Hiroshima Citizens Hosp, Dept Surg, Hiroshima, Japan

来源：

INTERNAL MEDICINE | 2019年 / 58卷 / 20期

关键词：

polyarteritis nodosa; hypereosinophilic syndrome; medium-sized vasculitis; colon; eosinophilia; acute surgical abdomen; SYSTEMIC-NECROTIZING-VASCULITIDES; DEEP-VEIN THROMBOSIS; HYPEREOSINOPHILIC SYNDROME; PULMONARY-EMBOLISM; STRAUSS-SYNDROME; GRANULOMATOSIS; CLASSIFICATION; ENHANCEMENT; CRITERIA;

D O I：

10.2169/internalmedicine.2802-19

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 45-year-old man was admitted with acute abdominal pain and eosinophilia. Abdominal computed tomography revealed thickness of the ascending and transverse colon with decreased contrast enhancement and a small amount of ascites. In an emergency operation, the necrotic colon was resected. Histopathology showed subserous medium-sized arteritis with abundant eosinophil infiltrates and thrombosis in the portal vein branches. He was diagnosed with polyarteritis nodosa (PAN), and immunosuppressive therapy improved his condition. Two years later, the disease recurred with ischemic cutaneous lesions and marked eosinophilia. Our experience suggests that marked eosinophilia in PAN may imply severe organ involvement, including gastrointestinal necrosis, as well as the association of venous thrombosis.

引用

页码：3051 / 3055

页数：5

共 21 条

[21] Takayasu arteritis (TA) first presenting with intestinal ischemia: a case report and review of gastrointestinal tract involvement (ischemic and non-ischemic) associated with TA
Misra, Durga Prasanna
Krishnan, Nagarajan
Gochhait, Debasis
Emmanuel, Dantis
Negi, Vir Singh
RHEUMATOLOGY INTERNATIONAL, 2017, 37 (01) : 169 - 175

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