Recent Developments in Polyene Cyclizations and Their Applications in Natural Product Synthesis

被引：80

作者：

Barrett, Anthony G. M. ^{[1
]}

Ma, Tsz-Kan ^{[1
]}

Mies, Thomas ^{[1
]}

机构：

[1] Imperial Coll London, Dept Chem, Mol Sci Res Hub, White City Campus,Wood Lane, London W12 0BZ, England

来源：

SYNTHESIS-STUTTGART | 2019年 / 51卷 / 01期

关键词：

polyene cyclization; cascade reaction; carbon-carbon bond formation; natural products; total synthesis; ENANTIOSELECTIVE BIOMIMETIC CYCLIZATION; ASYMMETRIC TOTAL-SYNTHESIS; CATALYZED CYCLOISOMERIZATION; TERPENOID POLYALKENES; BIOORGANIC CHEMISTRY; CASCADE CYCLIZATIONS; RADICAL CATIONS; POLYCYCLIZATION; ENTRY; CONSTRUCTION;

D O I：

10.1055/s-0037-1610382

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cascade polyene cyclization reactions are highly efficient and elegant bioinspired transformations that involve simultaneous multiple bond constructions to rapidly generate complex polycyclic molecules. This review summarizes the most prominent work on a variety of cationic and radical cascade cyclizations and their applications in natural product synthesis published between 2014 and 2018.

引用

页码：67 / 82

页数：16

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