Cell receptors for picornaviruses as determinants of cell tropism and pathogenesis

被引：75
作者：
Evans, DJ [1 ]
Almond, JW [1 ]
机构：
[1] Univ Reading, Sch Anim & Microbial Sci, Div Microbiol, Reading RG6 5AJ, Berks, England
来源：
TRENDS IN MICROBIOLOGY | 1998年 / 6卷 / 05期
基金：
英国医学研究理事会;
关键词：
D O I：
10.1016/S0966-842X(98)01263-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent studies have identified at least nine distinct receptors used by the picornaviruses for cell entry. Does the evolution of receptor usage correlate with the different tropisms observed in this group of viruses, and does this influence pathogenesis, or is it the consequence of another selection mechanism that favours virus survival?.
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收藏
页码：198 / 202
页数：5
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