Prevalence of stroke and myocardial infarction among patients with deteriorated GFR

- OBJECTIVE: Serval modifiable risk factors have been linked to stroke and myocardial infarction, including chronic Kendy disease. This study aimed to assess the prevalence of stroke and myocardial infarction among patients with deteriorated GFR (GFR < 60 mL/min). PATIENTS AND METHODS: A total of 1185 Saudi participants were enrolled during a cross-sectional survey conducted in Hai'l region, Northern Saudi Arabia. Volunteers were enrolled based on their GFR estimation. Only those with Stage III, Stage IV, or Stage V CKD were included. RESULTS: The overall prevalence of stroke was 2.4%. The risk of stroke associated with deteriorated GFR, the relative risk (RR) and the 95% confidence interval (95% CI), RR (95% CI) = 2.1371 (0.9804-4.6584), p = 0.0561. The prevalence rates of males and females were 3.7% and 1.2%, respectively. The overall prevalence of myocardial infarctions was 3.2% (4.7% in males and 2% in females).CONCLUSIONS: Deteriorated GFR <60 mL/ min is significantly associated with stroke and myocardial infarction. Stroke and MI are more prevalent among men than women. Stroke and MI are more prevalent in middle-aged adults and older individuals.