Macrophages Instruct Aberrant Glycosylation in Colon Cancer by Chemokine and Cytokine Signals

被引：6
作者：
Bronte, Vincenzo [1 ]
机构：
[1] Verona Univ, Dept Med, Verona, Italy
来源：
CANCER IMMUNOLOGY RESEARCH | 2020年 / 8卷 / 02期
关键词：
D O I：
10.1158/2326-6066.CIR-19-1005
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Myeloid cells can alter diverse molecular and metabolic pathways in cancer cells, contributing to their survival, migration, and resistance to chemotherapy and immune attack. The results by Kvorjak and colleagues unveil a novel circuit whereby altered glycosylation in epithelial cells promotes the pathogenesis of ulcerative colitis and colitisassociated colon cancer, via the production of IL13 and CCL17 by M2-polarized macrophages.
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收藏
页码：160 / 160
页数：1
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