Ring- closing metathesis of unprotected peptides in water

被引：21

作者：

Masuda, Shun ^{[1
]}

Tsuda, Shugo ^{[1
]}

Yoshiya, Taku ^{[1
]}

机构：

[1] Peptide Inst Inc, Ibaraki, Osaka 5670085, Japan

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2018年 / 16卷 / 48期

关键词：

OLEFIN-METATHESIS; CROSS-METATHESIS; CATALYSTS; ANALOGS;

D O I：

10.1039/c8ob02778a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring-closing metathesis (RCM) is an attractive reaction for the preparation of artificially designed peptides. Until now, RCM has been used for fully or partially protected peptides. Herein, the first RCM of unprotected peptides in water was achieved using a water-soluble Ru catalyst.

引用

页码：9364 / 9367

页数：4

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