Necrosis of uveal melanoma post-COVID-19 vaccination

被引：3
作者：
Wagle, Ajeet M. [1 ,2 ,3 ]
Wu, Bing Cheng [4 ]
Gopal, Lingam [5 ]
Sundar, Gangadhara [5 ]
机构：
[1] Natl Univ Singapore, Natl Univ Hosp, Int Eye Cataract Retina Ctr, Mt Elizabeth Med Ctr, Singapore, Singapore
[2] Natl Univ Singapore, Natl Univ Hosp, Farrer Pk Med Ctr, Singapore, Singapore
[3] Natl Univ Singapore, Natl Univ Hosp, Khoo Teck Puat Hosp, Dept Ophthalmol & Visual Sci, Singapore, Singapore
[4] Natl Univ Singapore, Natl Univ Hosp, Dept Pathol, Singapore, Singapore
[5] Natl Univ Singapore, Natl Univ Hosp, Dept Ophthalmol, Singapore, Singapore
来源：
INDIAN JOURNAL OF OPHTHALMOLOGY | 2022年 / 70卷 / 05期
关键词：
COVID-19; vaccination; necrotic melanoma; spontaneous necrosis; uveal melanoma on images malignancy; CHOROIDAL MELANOMA;
D O I：
10.4103/ijo.IJO_3040_21
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
A 49-year-old Indian male presented with rapidly progressive vision loss 1 day after receiving the second dose of BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine (Pfizer-BioNTech, NY, USA). The eye had secondary angle closure glaucoma, bullous retinal detachment, and massive intraocular hemorrhage. Ultrasound showed an ill-defined subretinal mass with moderate internal reflectivity. Magnetic resonance imaging (MRI) confirmed an enhancing heterogeneous subretinal mass. Histopathology showed a necrotic melanocytic lesion arising from the posterior edge of the ciliary body and choroid. Necrotic uveal melanoma was confirmed after expert histopathology opinion. Uveal melanomas can rarely present with tumor necrosis following mRNA COVID-19 vaccination.
引用
收藏
页码：1837 / 1840
页数：4
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