Structural and functional characterization of polyphenols isolated from acerola (Malpighia emarginata DC.) fruit

被引:116
作者
Hanamura, T
Hagiwara, T
Kawagishi, H
机构
[1] Nichirei Corp, Proc Foods Co, Div Res & Dev, Mihama Ku, Chiba 2618545, Japan
[2] Shizuoka Univ, Fac Agr, Dept Appl Biol Chem, Shizuoka 4228529, Japan
关键词
acerola; polyphenol; diabetes; alpha-glucosidase; advanced glycation end products;
D O I
10.1271/bbb.69.280
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two anthocyanins, cyanidin-3-alpha-O-rhamnoside (C3R) and pelargonidin-3-alpha-O-rhamnoside (M), and quercitrin (quercetin-3-alpha-O-rhamnoside), were isolated from acerola (Malpighia emarginata DC.) fruit. These polyphenols were evaluated based on the functional properties associated with diabetes mellitus or its complications, that is, on the radical scavenging activity and the inhibitory effect on both et-glucosidase and advanced glycation end product (AGE) formation. OR and quercitrin revealed strong radical scavenging activity. While the inhibitory profiles of isolated polyphenols except quercitrin towards alpha-glucosidase activity were low, all polyphenols strongly inhibited AGE formation.
引用
收藏
页码:280 / 286
页数:7
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