Procurement strategies for combined multiorgan and composite tissues for transplantation
被引:11
作者:
Datta, Neha
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机构:
Univ Calif Los Angeles, Dept Surg, Sect Reconstruct Transplantat, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Surg, Sect Reconstruct Transplantat, Los Angeles, CA 90095 USA
Datta, Neha
[1
]
Yersiz, Hasan
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机构:
Univ Calif Los Angeles, Pfleger Liver Inst, Dumont UCLA Liver Canc & Transplant Ctr, Dept Surg, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Surg, Sect Reconstruct Transplantat, Los Angeles, CA 90095 USA
Yersiz, Hasan
[2
]
Kaldas, Fady
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机构:
Univ Calif Los Angeles, Pfleger Liver Inst, Dumont UCLA Liver Canc & Transplant Ctr, Dept Surg, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Surg, Sect Reconstruct Transplantat, Los Angeles, CA 90095 USA
Kaldas, Fady
[2
]
Azari, Kodi
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机构:
Univ Calif Los Angeles, Dept Surg, Sect Reconstruct Transplantat, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Orthoped Surg, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Dept Surg, Sect Reconstruct Transplantat, Los Angeles, CA 90095 USA
Azari, Kodi
[1
,3
]
机构:
[1] Univ Calif Los Angeles, Dept Surg, Sect Reconstruct Transplantat, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Pfleger Liver Inst, Dumont UCLA Liver Canc & Transplant Ctr, Dept Surg, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Dept Orthoped Surg, Los Angeles, CA 90095 USA
Purpose of review The purpose of this article is to identify the unique aspects of combined multiorgan and vascularized composite allograft (VCA) procurement from deceased donors and outline the steps essential for success. Recent findings Transplantation of nonsolid organ composite tissues is becoming a viable option for reconstruction of massive tissue defects. With the United Network for Organ Sharing designation of VCAs as organs, placing them under the domain of the Organ Procurement and Transplantation Network, a systematic method for combined solid organ and VCA procurement is required. Several centers have reported experience with successful procurement strategies including sequential and simultaneous retrievals. The published literature describing donor screening, sequence of procurement with relation to solid organs and allocation is reviewed. Summary With the 2013 classification of VCAs as organs, the Organ Procurement and Transplantation Network and United Network for Organ Sharing are better suited to aligning procurement and allocation policies. As VCA transplantation becomes more commonplace, protocol guidelines will ensure smooth integration with existing procurement infrastructure.