An introduction to molecular replacement

被引：66

作者：

Evans, Philip

McCoy, Airlie

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 0QH, England

[2] Univ Cambridge, Inst Med Res, Dept Haematol, Cambridge CB2 2XY, England

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2008年 / 64卷

基金：

英国医学研究理事会;

关键词：

molecular replacement is fundamentally a simple trial-anderror; method of solving crystal structures when a suitable; related model is available. The underlying simplicity of the; method is often obscured by the mathematical trickery; required to make the searches computationally tractable. This; introduction sketches the essential issues in molecular; replacement without going into technical details. General; search strategies are discussed and the alternative Patterson; and likelihood approaches are outlined;

D O I：

10.1107/S0907444907051554

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1 / 10

页数：10

共 35 条

[1] CALCULATION OF AN OMIT MAP [J].

BHAT, TN .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1988, 21 :279-281

[2]

BRICOGNE G, 1992, P CCP4 STUD WEEK MOL, P62

[3] EXTENSION OF MOLECULAR REPLACEMENT - A NEW SEARCH STRATEGY BASED ON PATTERSON CORRELATION REFINEMENT [J].

BRUNGER, AT .

ACTA CRYSTALLOGRAPHICA SECTION A, 1990, 46 :46-57

[4] Molecular replacement using genetic algorithms [J].

Chang, G ;

Lewis, M .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1997, 53 :279-289

[5]

CROWTHER RA, 1972, MOL REPLACEMENT METH, P173

[6] Dealing with structural variability in molecular replacement and crystallographic refinement through normal-mode analysis [J].

Delarue, Marc .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2008, 64 :40-48

[7] Rotations and rotation matrices [J].

Evans, PR .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2001, 57 :1355-1359

[8] EXPERIENCES WITH A NEW TRANSLATION-FUNCTION PROGRAM [J].

FUJINAGA, M ;

READ, RJ .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1987, 20 :517-521

[9] Multidimensional molecular replacement [J].

Glykos, NM ;

Kokkinidis, M .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2001, 57 :1462-1473

[10] A TRANSLATION FUNCTION COMBINING PACKING AND DIFFRACTION INFORMATION - AN APPLICATION TO LYSOZYME (HIGH-TEMPERATURE FORM) [J].

HARADA, Y ;

LIFCHITZ, A ;

BERTHOU, J ;

JOLLES, P .

ACTA CRYSTALLOGRAPHICA SECTION A, 1981, 37 (MAY) :398-406

← 1 2 3 4 →