Novel composite poly (4-vinylpyridine)/polypropylene membranes with recognition properties for (S)-naproxen

被引：47

作者：

Donato, L ^{[1
]}

Figoli, A ^{[1
]}

Drioli, E ^{[1
]}

机构：

[1] Univ Calabria, CNR, ITM, Res Inst Membrane Technol, I-87030 Arcavacata Di Rende, CS, Italy

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2005年 / 37卷 / 05期

关键词：

molecular imprinting; composite membrane; photo-copolymerization; enantioseparation; selective transport;

D O I：

10.1016/j.jpba.2004.09.020

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In the last few years, molecular imprinting technology has entered in different fields of chemistry, biochemistry, biotechnology and medicine. The technique allows us to introduce the molecular memory of the substrate to be recognized in a polymeric material during its preparation. In the present paper, molecularly imprinted enantioselective polymer membranes were prepared by photo-copolymerization of commercial polypropylene membranes with the functional monomer 4-vinylpyridine. The (S)-naproxen was used as a template molecule. Enantioselectivity studies in a dead-end filtration system showed the recognition properties of the imprinted membranes, which exhibited a selective transport of the (S)-enantiomer. © 2004 Elsevier B.V. All rights reserved.

引用

页码：1003 / 1008

页数：6

共 30 条

[1] From ultrafiltration to nanofiltration hollow fiber membranes:: a continuous UV-photografting process [J].