Case report - Malignancy in pigmented villonodular synovitis

被引:36
作者
Kalil, RK
Unni, KK
机构
[1] Mayo Clin & Mayo Fdn, Dept Lab Med & Pathol, Rochester, MN 55905 USA
[2] Sarah Network Hosp Locomotor Syst, Dept Pathol, Brasilia, DF, Brazil
关键词
pigmented villonodular synovitis; giant cell tumor of tendon sheath; malignant tumor; synovium;
D O I
10.1007/s002560050405
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Malignant pigmented villonodular synovitis is an extremely rare and controversial disease. We describe malignant change in pigmented villonodular synovitis of the ankle in a patient with an unusually long clinical history. Symptoms began at age 21, metastatic disease developed at age 85, and the patient died 1 year later. The histologic appearance of the malignant tumor differed from that in most reported cases, in that spindle-shaped cells predominated. Lymph node metastasis also developed, a feature uncommon to soft tissue sarcomas.
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页码:392 / 395
页数:4
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