Use of safety-modified retroviruses to introduce chemotherapy resistance sequences into normal hematopoietic cells for chemoprotection during the therapy of breast cancer: A pilot trial

被引:26
作者
Deisseroth, AB [1 ]
Holmes, F [1 ]
Hortobagyi, G [1 ]
Champlin, R [1 ]
机构
[1] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT MED ONCOL,HOUSTON,TX 77030
关键词
D O I
10.1089/hum.1996.7.3-401
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
[No abstract available]
引用
收藏
页码:401 / 416
页数:16
相关论文
共 19 条
[1]   EXPRESSION OF HUMAN ADENOSINE-DEAMINASE IN MURINE HEMATOPOIETIC-CELLS [J].
BELMONT, JW ;
MACGREGOR, GR ;
WAGERSMITH, K ;
FLETCHER, FA ;
MOORE, KA ;
HAWKINS, D ;
VILLALON, D ;
CHANG, SMW ;
CASKEY, CT .
MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (12) :5116-5125
[2]  
BODINE D, 1992, UCLA GEN THER M COPP
[3]   DEVELOPING NEW DRUGS FOR OVARIAN-CANCER - A CHALLENGING TASK IN A CHANGING REALITY [J].
CANETTA, RM ;
CARTER, SK .
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1984, 107 (02) :111-124
[4]  
CLAXTON D, 1991, HUM GENE THER, V1, P317
[5]  
DEISSEROTH AB, 1991, HUM GENE THER, V2, P359
[6]   2 MEMBERS OF THE MOUSE MDR GENE FAMILY CONFER MULTIDRUG RESISTANCE WITH OVERLAPPING BUT DISTINCT DRUG SPECIFICITIES [J].
DEVAULT, A ;
GROS, P .
MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (04) :1652-1663
[7]   USE OF CELL-FREE RETROVIRAL VECTOR PREPARATIONS FOR TRANSDUCTION OF CELLS FROM THE MARROW OF CHRONIC PHASE AND BLAST CRISIS CHRONIC MYELOGENOUS LEUKEMIA PATIENTS AND FROM NORMAL INDIVIDUALS [J].
ETKIN, M ;
FILACCIO, M ;
ELLERSON, D ;
SUH, SP ;
CLAXTON, D ;
GAOZZA, E ;
BRENNER, M ;
MOEN, R ;
BELMONT, J ;
MOORE, KA ;
MOSELEY, AM ;
READING, C ;
KHOURI, I ;
TALPAZ, M ;
KANTARJIAN, H ;
DEISSERROTH, A .
HUMAN GENE THERAPY, 1992, 3 (02) :137-145
[8]   EXPRESSION OF A MULTIDRUG RESISTANCE GENE IN HUMAN CANCERS [J].
GOLDSTEIN, LJ ;
GALSKI, H ;
FOJO, A ;
WILLINGHAM, M ;
LAI, SL ;
GAZDAR, A ;
PIRKER, R ;
GREEN, A ;
CRIST, W ;
BRODEUR, GM ;
LIEBER, M ;
COSSMAN, J ;
GOTTESMAN, MM ;
PASTAN, I .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1989, 81 (02) :116-124
[9]   HUMAN-GENE TRANSFER - CHARACTERIZATION OF HUMAN TUMOR-INFILTRATING LYMPHOCYTES AS VEHICLES FOR RETROVIRAL-MEDIATED GENE-TRANSFER IN MAN [J].
KASID, A ;
MORECKI, S ;
AEBERSOLD, P ;
CORNETTA, K ;
CULVER, K ;
FREEMAN, S ;
DIRECTOR, E ;
LOTZE, MT ;
BLAESE, RM ;
ANDERSON, WF ;
ROSENBERG, SA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (01) :473-477
[10]   LONG-TERM EXPRESSION OF HUMAN ADENOSINE-DEAMINASE IN MICE TRANSPLANTED WITH RETROVIRUS-INFECTED HEMATOPOIETIC STEM-CELLS [J].
LIM, B ;
APPERLEY, JF ;
ORKIN, SH ;
WILLIAMS, DA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (22) :8892-8896