Investigation of Size Dependence on Sensitivity for Nanowire FET Biosensors

被引:27
作者
Ahn, Jae-Hyuk [1 ]
Choi, Sung-Jin [1 ]
Han, Jin-Woo [2 ]
Park, Tae Jung [3 ]
Lee, Sang Yup [3 ,4 ,5 ,6 ,7 ]
Choi, Yang-Kyu [1 ]
机构
[1] Korea Adv Inst Sci & Technol, Dept Elect Engn, Taejon 305701, South Korea
[2] NASA, Ames Res Ctr, Ctr Nanotechnol, Moffett Field, CA 94035 USA
[3] Korea Adv Inst Sci & Technol, BioProc Engn Res Ctr, Ctr Syst & Synthet Biotechnol, Inst BioCentury, Taejon 305701, South Korea
[4] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, Taejon 305701, South Korea
[5] Korea Adv Inst Sci & Technol, Bioinformat Res Ctr, Taejon 305701, South Korea
[6] Korea Adv Inst Sci & Technol, Dept Biol Sci, Taejon 305701, South Korea
[7] Korea Adv Inst Sci & Technol, Dept Bio & Brain Engn, Taejon 305701, South Korea
基金
新加坡国家研究基金会;
关键词
Biosensor; capacitive model; double gate (DG); field-effect transistor (FET); nanowire (NW); LABEL-FREE DETECTION; ELECTRICAL DETECTION; SILICON NANOWIRES; CARBON NANOTUBES; DNA HYBRIDIZATION; NANOSENSORS; DEVICES; SENSORS; MOSFETS; SURFACE;
D O I
10.1109/TNANO.2011.2157519
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Label-free electrical detection of biomolecules is demonstrated with a double-gate (DG) nanowire (NW) field-effect transistor (FET). Experimental results confirm that detection sensitivity is favorably improved by the increment of NW size in the DG-NWFET, whereas it is enhanced by the decrement of NW size in a conventional single-gate (SG) NWFET. Sensitivity improvement by the augmentation of the NW size in the DG-FET paves the way to overcome technical challenges we face in achieving ultimate miniaturization of the NW size in the SG-FET. This result is comprehensively understood by simple capacitive modeling. The proposed model explains the observed experimental data and provides a design guideline for highly sensitive NW biosensors.
引用
收藏
页码:1405 / 1411
页数:7
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