Rupestines F-M, New Guaipyridine Sesquiterpene Alkaloids from Artemisia rupestris

被引：30

作者：

He, Fei ^{[1
,2
]}

Nugroho, Alfarius Eko ^{[1
]}

Wong, Chin Piow ^{[1
]}

Hirasawa, Yusuke ^{[1
]}

Shirota, Osamu ^{[3
]}

Morita, Hiroshi ^{[1
]}

Aisa, Haji Akber ^{[2
]}

机构：

[1] Hoshi Univ, Fac Pharmaceut Sci, Shinagawa Ku, Tokyo 1428501, Japan

[2] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Chem Plant Resources Arid Reg, Urumqi 830011, Xinjiang, Peoples R China

[3] Tokushima Bunri Univ, Fac Pharmaceut Sci, Sanuki, Kagawa 7692193, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2012年 / 60卷 / 02期

基金：

美国国家科学基金会;

关键词：

Artemisia rupestris; rupestine; guaipyridine sesquiterpene alkaloid; circular dichroism; absolute configuration; MOLECULAR-FORCE FIELD; VAN-DER-WAALS; PARAMETERS; MECHANICS; DENSITY; MMFF94;

D O I：

10.1248/cpb.60.213

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Eight new guaipyridine sesquiterpene alkaloids, rupestines F-M (1-8) were isolated from the leaves of Artemisia rupestris and their structures were elucidated on the basis of 2D-NMR data. The absolute configurations of 1-8 have been assigned by comparison of their experimental and calculated circular dichroism (CD) spectra.

引用

页码：213 / 218

页数：6

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