Bacterial solutions to the iron supply problem

被引：316

作者：

Braun, V ^{[1
]}

Killmann, H ^{[1
]}

机构：

[1] Univ Tubingen, Lehrstuhl Mikrobiol Membranphysiol, D-72076 Tubingen, Germany

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1999年 / 24卷 / 03期

关键词：

D O I：

10.1016/S0968-0004(99)01359-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The insolubility of Fe3+ necessitates special mechanisms for iron acquisition in most organisms. Bacteria use siderophores to chelate Fe3+ andiron in heme, hemoglobin, transferrin and lactoferrin, and employ novel mechanisms for receptor-dependent iron transport and iron-regulated gene expression. These mechanisms involve transfer of energy from the cytoplasmic membrane to the outer membrane to drive active transport and might induce transcription of transport genes by transmitting a signal from the cell surface.

引用

页码：104 / 109

页数：6

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