Quantitation of 14-3-3 and neuron-specific enolase proteins in CSF in Creutzfeldt-Jakob disease

被引：61

作者：

Aksamit, AJ

Preissner, CM

Homburger, HA

机构：

[1] Mayo Clin, Dept Neurol, Rochester, MN 55905 USA

[2] Mayo Clin, Dept Lab Med & Pathol, Rochester, MN 55905 USA

来源：

NEUROLOGY | 2001年 / 57卷 / 04期

关键词：

D O I：

10.1212/WNL.57.4.728

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

CSF 14-3-3 and neuron-specific enolase (NSE) proteins were quantitated from patients who had Creutzfeldt-Jakob disease (CJD) or other rapidly dementing disorders initially considered to be CJD. Thirty-one patients were diagnosed as having CJD among 152 studied. CSF 14-3-3 values more than 8 ng/mL correlated with CJD. CSF NSE values less than 30 ng/mL and 14-3-3 values less than 8 ng/mL made a diagnosis of CJD unlikely, but did not exclude it.

引用

页码：728 / 730

页数：3

共 9 条

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