Rhodium-Catalyzed Asymmetric [2+2+2] Cyclization of 1,6-Enynes and Aldehydes

被引：30

作者：

Ishida, Mana ^{[1
]}

Shibata, Yu ^{[1
]}

Noguchi, Keiichi ^{[2
]}

Tanaka, Ken ^{[1
]}

机构：

[1] Tokyo Univ Agr & Technol, Dept Appl Chem, Grad Sch Engn, Koganei, Tokyo 1848588, Japan

[2] Tokyo Univ Agr & Technol, Instrumentat Anal Ctr, Koganei, Tokyo 1848588, Japan

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 45期

关键词：

aldehydes; asymmetric catalysis; cyclization; enynes; rhodium; CARBOCYCLIZATION REACTIONS; UNSATURATED-HYDROCARBONS; ACYL PHOSPHONATES; CYCLOADDITION; CONSTRUCTION; 1,6-DIYNES; INSERTION; KETONES; DIYNES; ENYNES;

D O I：

10.1002/chem.201102418

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric catalysis: The rhodium-catalyzed asymmetric [2+2+2] cyclization of 1,6-enynes and aldehydes was achieved by using a cationic rhodium(I)/(R)-binap complex as a catalyst (see scheme; cod=1,5-cyclooctadiene). Coordination of the substrate heteroatom to the cationic rhodium plays an important role in this cyclization reaction. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：12578 / 12581

页数：4

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