A simple and convenient synthesis of 3-[5-(trifluoromethyl)-1,2,3-triazol-4-yl]cinnamic acids from 4-aryl-6-(trifluoromethyl)-2H-pyran-2-ones and sodium azide

被引：11

作者：

Usachev, Boris I. ^{[1
]}

Usachev, Sergey A. ^{[1
]}

Roeschenthaler, Gerd-Volker ^{[2
]}

Sosnovskikh, Vyacheslav Ya ^{[1
]}

机构：

[1] Ural Fed Univ, Dept Chem, Ekaterinburg 620083, Russia

[2] Jacobs Univ Bremen gGmbH, Sch Sci & Engn, D-28759 Bremen, Germany

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 50期

关键词：

Trifluoromethylated; 2-pyrones; Sodium azide; Trifluoromethylated triazoles; Cinnamic acid derivatives; Malonic acid derivatives; BUILDING-BLOCKS; 2H-PYRAN-2-ONES; 1,2,3-TRIAZOLES; CHEMISTRY; ANALOGS;

D O I：

10.1016/j.tetlet.2011.09.149

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Aryl-6-(trifluoromethyl)-2H-pyran-2-ones and ethyl 4-aryl-6-(trifluoromethyl)-2-oxo-2H-pyran-3-carboxylates react with sodium azide to produce highly functionalized CF3-1,2,3-triazoles: 3-[5-(trifluoromethyl)-1,2,3-triazol-4-yl]cinnamic acids and monoethyl esters of [5-(trifluoromethyl)-1,2,3-triazol-4-yl]arylmethylidene malonic acids. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：6723 / 6725

页数：3

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