Measurements of wavelength dependent scattering and backscattering coefficients by low-coherence spectroscopy

被引：30

作者：

Bosschaart, Nienke ^{[1
]}

Faber, Dirk J. ^{[1
]}

van Leeuwen, Ton G. ^{[1
,2
]}

Aalders, Maurice C. G. ^{[1
]}

机构：

[1] Univ Amsterdam, Biomed Engn & Phys Acad Med Ctr, NL-1100 DE Amsterdam, Netherlands

[2] Univ Twente, Biomed Photon Imaging Grp, MIRA Inst Biomed Technol & Tech Med, NL-7500 AE Enschede, Netherlands

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2011年 / 16卷 / 03期

关键词：

spectroscopy; scattering; backscattering; coherence; tissues; Mie theory; TOMOGRAPHY; ABSORPTION; INTERFEROMETRY; SUSPENSIONS; MEDIA;

D O I：

10.1117/1.3553005

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Quantitative measurements of scattering properties are invaluable for optical techniques in medicine. However, noninvasive, quantitative measurements of scattering properties over a large wavelength range remain challenging. We introduce low-coherence spectroscopy as a noninvasive method to locally and simultaneously measure scattering mu(s) and backscattering mu(b) coefficients from 480 to 700 nm with 8 nm spectral resolution. The method is tested on media with varying scattering properties (as = 1 to 34 mm(-1) and mu(b) = 2.10(-6) to 2.10(-3) mm(-1)), containing different sized polystyrene spheres. The results are in excellent agreement with Mie theory. (C) 2011 society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3553005]

引用

页数：3

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