SPIRONOLACTONE SUPRESSES NF-⊠B AND AP-1 INFLAMMATORY SIGNALING INDEPENDENT OF THE MINERALOCORTICOID RECEPTOR

被引：0
|
作者：
Elinoff, Jason M. [1 ]
Doughtery, Edward J. [1 ]
Solomon, Michael [1 ]
Danner, Robert L. [1 ]
机构：
[1] NIH, Dept Crit Care Med, Mark O Hatfield Clin Res Ctr, Bethesda, MD 20892 USA
来源：
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2014年 / 63卷 / 12期
关键词：
D O I：
10.1016/S0735-1097(14)61503-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1263-211
引用
收藏
页码：A1502 / A1502
页数：1
相关论文
共 50 条
  • [31] NF-κB and AP-1 as molecular targets for chemoprevention with EGCG, a review
    Young-Joon Surh
    Environmental Chemistry Letters, 2006, 4 : 137 - 141
  • [32] Interaction of glucocorticoid receptor isoforms with transcription factors AP-1 and NF-κB:: lack of effect of glucocorticoid receptor β
    Brogan, IJ
    Murray, IA
    Cerillo, G
    Needham, M
    White, A
    Davis, JRE
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1999, 157 (1-2) : 95 - 104
  • [33] Expression of transcription factors NF-κB and AP-1 in nasal polyposis
    Valera, F. C. P.
    Queiroz, R.
    Scrideli, C.
    Tone, L. G.
    Anselmo-Lima, W. T.
    CLINICAL AND EXPERIMENTAL ALLERGY, 2008, 38 (04): : 579 - 585
  • [34] Liver NF-κB and AP-1 DNA Binding in Obese Patients
    Videla, Luis A.
    Tapia, Gladys
    Rodrigo, Ramon
    Pettinelli, Paulina
    Haim, Daniela
    Santibanez, Catherine
    Veronica Araya, A.
    Smok, Gladys
    Csendes, Attila
    Gutierrez, Luis
    Rojas, Jorge
    Castillo, Jaime
    Korn, Owen
    Maluenda, Fernando
    Diaz, Juan C.
    Rencoret, Guillermo
    Poniachik, Jaime
    OBESITY, 2009, 17 (05) : 973 - 979
  • [35] Oxidative stress and gene expression:: The AP-1 and NF-κB connections
    Karin, M
    Takahashi, T
    Kapahi, P
    Delhase, M
    Chen, Y
    Makris, C
    Rothwarf, D
    Baud, V
    Natoli, G
    Guido, F
    Li, NX
    BIOFACTORS, 2001, 15 (2-4) : 87 - 89
  • [36] Prenylated Stilbenoids Affect Inflammation by Inhibiting the NF-κB/AP-1 Signaling Pathway and Cyclooxygenases and Lipoxygenase
    Hosek, Jan
    Lelakova, Veronika
    Bobal, Pavel
    Pizova, Hana
    Gazdova, Marketa
    Malanik, Milan
    Jakubczyk, Karolina
    Vesely, Ondrej
    Landa, Premysl
    Temml, Veronika
    Schuster, Daniela
    Prachyawarakorn, Vilailak
    Pailee, Phanruethai
    Ren, Gang
    Zpurny, Filip
    Oravec, Michal
    Smejkal, Karel
    JOURNAL OF NATURAL PRODUCTS, 2019, 82 (07): : 1839 - 1848
  • [37] Hypoxic suppression of E-coli-induced NF-κB and AP-1 transactivation by oxyradical signaling
    Matuschak, GM
    Lechner, AJ
    Chen, ZM
    Todi, S
    Doyle, TM
    Loftis, LL
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2004, 287 (02) : R437 - R445
  • [38] Sulfuretin suppresses inflammatory responses by blocking the NF-κB and AP-1 translocation signaling pathways in BV-2 microglial cells
    Ma, S. -X.
    Kwon, S. -H.
    Hong, S. -I.
    Jung, Y. -H.
    Hwang, J. -Y.
    Kim, J. -S.
    Seo, J. -Y.
    Lee, J. -H.
    Lee, S. -Y.
    Jang, C. -G.
    JOURNAL OF NEUROCHEMISTRY, 2014, 130 : 52 - 52
  • [39] Overexpression of the human glucocorticoid receptor α and β isoforms inhibits AP-1 and NF-κB activities hormone independently
    Gougat, C
    Jaffuel, D
    Gagliardo, R
    Henriquet, C
    Bousquet, J
    Demoly, P
    Mathieu, M
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2002, 80 (05): : 309 - 318
  • [40] Glucocorticoid receptor represses the NF-κB and AP-1 pathways via O-GlcNAc transferase
    Yang, X
    MOLECULAR BIOLOGY OF THE CELL, 2004, 15 : 358A - 358A
12345