Nonmotor Symptoms in Parkinson's Disease

被引:44
作者
Stacy, Mark [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Neurol, Durham, NC 27705 USA
关键词
impulse control disorder; nonmotor; Parkinson; psychosis; COGNITIVE IMPAIRMENT; PATIENT QUESTIONNAIRE; DAYTIME SLEEPINESS; PSYCHOTIC SYMPTOMS; DOUBLE-BLIND; LEWY BODIES; WEARING-OFF; DEMENTIA; DYSFUNCTION; RIVASTIGMINE;
D O I
10.3109/00207454.2011.620196
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The recognition and treatment of nonmotor symptoms are increasingly emphasized in the care of Parkinson's disease (PD) patients. This manuscript will review signs and symptoms localized, generally, to the cortex, basal ganglia, brainstem, spinal cord, and peripheral nervous system. Cortical manifestations include dementia, mild cognitive impairment, and psychosis. Apathy, restlessness (akathisia), and impulse control disorders will be linked as basal ganglia symptoms. Symptoms attributed to the brainstem comprise depression, anxiety, and sleep disorders. Peripheral nervous system disturbances may lead to orthostatic hypotension, constipation, pain, and sensory disturbances.
引用
收藏
页码:9 / 17
页数:9
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