Targeted gene disruption in somatic zebrafish cells using engineered TALENs

被引：437

作者：

Sander, Jeffry D. ^{[1
,2
,3
]}

Cade, Lindsay ^{[4
,5
]}

Khayter, Cyd ^{[1
,2
]}

Reyon, Deepak ^{[6
]}

Peterson, Randall T. ^{[4
,5
,7
]}

Joung, J. Keith ^{[1
,2
,3
]}

Yeh, Jing-Ruey J. ^{[4
,5
]}

机构：

[1] Massachusetts Gen Hosp, Mol Pathol Unit, Ctr Canc Res, Charlestown, MA USA

[2] Massachusetts Gen Hosp, Ctr Computat & Integrat Biol, Charlestown, MA USA

[3] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

[4] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Charlestown, MA USA

[5] Harvard Univ, Sch Med, Dept Med, Boston, MA USA

[6] Iowa State Univ, Dept Genet Dev & Cell Biol, Interdept Grad Program Bioinformat & Computat Bio, Ames, IA USA

[7] Broad Inst, Cambridge, MA USA

来源：

NATURE BIOTECHNOLOGY | 2011年 / 29卷 / 08期

关键词：

ZINC-FINGER NUCLEASES; EFFECTORS;

D O I：

10.1038/nbt.1934

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：697 / 698

页数：2

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