共 310 条
Gene-environment interactions in Alzheimer disease: the emerging role of epigenetics
被引:107
作者:

Migliore, Lucia
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Pisa, Dept Translat Res & New Surg & Med Technol, Pisa, Italy
Univ Hosp Pisa, Dept Lab Med, Pisa, Italy Univ Pisa, Dept Translat Res & New Surg & Med Technol, Pisa, Italy

Coppede, Fabio
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Pisa, Dept Translat Res & New Surg & Med Technol, Pisa, Italy Univ Pisa, Dept Translat Res & New Surg & Med Technol, Pisa, Italy
机构:
[1] Univ Pisa, Dept Translat Res & New Surg & Med Technol, Pisa, Italy
[2] Univ Hosp Pisa, Dept Lab Med, Pisa, Italy
基金:
英国科研创新办公室;
关键词:
GENOME-WIDE ASSOCIATION;
ONE-CARBON METABOLISM;
INCREASES PRESENILIN EXPRESSION;
AMYLOID PRECURSOR PROTEIN;
GAMMA-SECRETASE ACTIVITY;
GLOBAL DNA METHYLATION;
S-ADENOSYL METHIONINE;
EARLY-LIFE EXPOSURE;
LEAD PB ALTERS;
OXIDATIVE STRESS;
D O I:
10.1038/s41582-022-00714-w
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Most cases of Alzheimer disease (AD) have a complex aetiology, probably involving multiple genetic and environmental factors. In this Review, the authors discuss how various environmental AD risk factors could induce epigenetic modifications of key AD-associated genes and pathways. With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex aetiology that is likely to involve multiple susceptibility genes and environmental factors. The role of environmental factors is difficult to determine and, until a few years ago, the molecular mechanisms underlying gene-environment (G x E) interactions in AD were largely unknown. Here, we review evidence that has emerged over the past two decades to explain how environmental factors, such as diet, lifestyle, alcohol, smoking and pollutants, might interact with the human genome. In particular, we discuss how various environmental AD risk factors can induce epigenetic modifications of key AD-related genes and pathways and consider how epigenetic mechanisms could contribute to the effects of oxidative stress on AD onset. Studies on early-life exposures are helping to uncover critical time windows of sensitivity to epigenetic influences from environmental factors, thereby laying the foundations for future primary preventative approaches. We conclude that epigenetic modifications need to be considered when assessing G x E interactions in AD.
引用
收藏
页码:643 / 660
页数:18
相关论文
共 310 条
[1]
Environmental Risk Factors for Early-Onset Alzheimer's Dementia and Frontotemporal Dementia: A Case-Control Study in Northern Italy
[J].
Adani, Giorgia
;
Filippini, Tommaso
;
Garuti, Caterina
;
Malavolti, Marcella
;
Vinceti, Giulia
;
Zamboni, Giovanna
;
Tondelli, Manuela
;
Galli, Chiara
;
Costa, Manuela
;
Vinceti, Marco
;
Chiari, Annalisa
.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,
2020, 17 (21)
:1-18

Adani, Giorgia
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Filippini, Tommaso
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Garuti, Caterina
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Malavolti, Marcella
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Vinceti, Giulia
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Modena & Reggio Emilia, Ctr Neurosci & Neurotechnol, Dept Biomed Metab & Neural Sci, I-41126 Modena, Italy
Modena Policlin Univ Hosp, Neurol Unit, I-41126 Modena, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

论文数: 引用数:
h-index:
机构:

Tondelli, Manuela
论文数: 0 引用数: 0
h-index: 0
机构:
Modena Policlin Univ Hosp, Neurol Unit, I-41126 Modena, Italy
Modena Local Hlth Author, Primary Care Dept, I-41124 Modena, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Galli, Chiara
论文数: 0 引用数: 0
h-index: 0
机构:
Modena Policlin Univ Hosp, Neurol Unit, I-41126 Modena, Italy
Modena Local Hlth Author, Primary Care Dept, I-41124 Modena, Italy
Univ Florence, Dept Neurosci Psychol Pharmacol & Child Hlth Neur, I-50139 Florence, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Costa, Manuela
论文数: 0 引用数: 0
h-index: 0
机构:
Carpi Hosp, Modena Local Hlth Author, Neurol Unit, I-41012 Carpi, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Vinceti, Marco
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy
Boston Univ, Dept Epidemiol, Sch Publ Hlth, Boston, MA 02118 USA Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy

Chiari, Annalisa
论文数: 0 引用数: 0
h-index: 0
机构:
Modena Policlin Univ Hosp, Neurol Unit, I-41126 Modena, Italy Univ Modena & Reggio Emilia, Environm Genet & Nutr Epidemiol Res Ctr CREAGEN, Dept Biomed Metab & Neural Sci, I-41125 Modena, Italy
[2]
Pesticides, cognitive functions and dementia: A review
[J].
Aloizou, Athina-Maria
;
Siokas, Vasileios
;
Vogiatzi, Christina
;
Peristeri, Eleni
;
Docea, Anca Oana
;
Petrakis, Demetrios
;
Provatas, Antonios
;
Folia, Vasiliki
;
Chalkia, Charikleia
;
Vinceti, Marco
;
Wilks, Martin
;
Izotov, Boris N.
;
Tsatsakis, Aristidis
;
Bogdanos, Dimitrios P.
;
Dardiotis, Efthimios
.
TOXICOLOGY LETTERS,
2020, 326
:31-51

Aloizou, Athina-Maria
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Siokas, Vasileios
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Vogiatzi, Christina
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Peristeri, Eleni
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Docea, Anca Oana
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Med & Pharm Craiova, Dept Toxicol, Craiova 200349, Romania Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Petrakis, Demetrios
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Crete, Toxicol Lab, Sch Med, Iraklion 71409, Crete, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Provatas, Antonios
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Folia, Vasiliki
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Chalkia, Charikleia
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Vinceti, Marco
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Modena & Reggio Emilia, Dept Biomed Metab & Neural Sci, Modena, Italy
Boston Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

论文数: 引用数:
h-index:
机构:

Izotov, Boris N.
论文数: 0 引用数: 0
h-index: 0
机构:
Sechenov Univ, Dept Analyt & Forens Med Toxicol, Moscow 119048, Russia Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Tsatsakis, Aristidis
论文数: 0 引用数: 0
h-index: 0
机构:
Sechenov Univ, Dept Analyt & Forens Med Toxicol, Moscow 119048, Russia
Univ Crete, Ctr Toxicol Sci & Res, Sch Med, Iraklion 71003, Crete, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Bogdanos, Dimitrios P.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Thessaly, Dept Rheumatol & Clin Immunol, Univ Gen Hosp Larissa, Fac Med,Sch Hlth Sci, Viopolis 40500, Larissa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece

Dardiotis, Efthimios
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
Univ Thessaly, Sch Hlth Sci, Fac Med, Larisa, Greece Univ Hosp Larissa, Dept Neurol, Neurogenet Lab, Larisa, Greece
[3]
Environmental Epigenetic Changes, as Risk Factors for the Development of Diseases in Children: A Systematic Review
[J].
Alvarado-Cruz, Isabel
;
Alegria-Torres, Jorge A.
;
Montes-Castro, Nereida
;
Jimenez-Garza, Octavio
;
Quintanilla-Vega, Betzabet
.
ANNALS OF GLOBAL HEALTH,
2018, 84 (02)
:212-224

Alvarado-Cruz, Isabel
论文数: 0 引用数: 0
h-index: 0
机构:
CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico

Alegria-Torres, Jorge A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Guanajuato, Pharm Dept, Guanajuato, Mexico CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico

Montes-Castro, Nereida
论文数: 0 引用数: 0
h-index: 0
机构:
CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico

Jimenez-Garza, Octavio
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Guanajuato, Hlth Sci Div, Leon Campus, Guanajuato, Mexico CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico

Quintanilla-Vega, Betzabet
论文数: 0 引用数: 0
h-index: 0
机构:
CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico CINVESTAV, Toxicol Dept, Mexico City, DF, Mexico
[4]
Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1
[J].
An, Yu
;
Feng, Lingli
;
Zhang, Xiaona
;
Wang, Ying
;
Wang, Yushan
;
Tao, Lingwei
;
Qin, Zhongsheng
;
Xiao, Rong
.
CLINICAL EPIGENETICS,
2019, 11 (01)

An, Yu
论文数: 0 引用数: 0
h-index: 0
机构:
Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China

Feng, Lingli
论文数: 0 引用数: 0
h-index: 0
机构:
Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China
Peking Univ, Hosp 1, Beijing, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China

Zhang, Xiaona
论文数: 0 引用数: 0
h-index: 0
机构:
Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China

Wang, Ying
论文数: 0 引用数: 0
h-index: 0
机构:
Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China

Wang, Yushan
论文数: 0 引用数: 0
h-index: 0
机构:
Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China

Tao, Lingwei
论文数: 0 引用数: 0
h-index: 0
机构:
Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China

Qin, Zhongsheng
论文数: 0 引用数: 0
h-index: 0
机构:
Jincheng Peoples Hosp, Jincheng, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China

Xiao, Rong
论文数: 0 引用数: 0
h-index: 0
机构:
Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China Capital Med Univ, Sch Publ Hlth, 10 Xitoutiao, Beijing 100069, Peoples R China
[5]
APOE Genotype and Alzheimer's Disease: The Influence of Lifestyle and Environmental Factors
[J].
Angelopoulou, Efthalia
;
Paudel, Yam Nath
;
Papageorgiou, Sokratis G.
;
Piperi, Christina
.
ACS CHEMICAL NEUROSCIENCE,
2021, 12 (15)
:2749-2764

Angelopoulou, Efthalia
论文数: 0 引用数: 0
h-index: 0
机构:
Natl & Kapodistrian Univ Athens, Med Sch, Dept Biol Chem, Athens 11527, Greece
Natl & Kapodistrian Univ Athens, Eginit Univ Hosp, Med Sch, Dept Neurol, Athens 11528, Greece Natl & Kapodistrian Univ Athens, Med Sch, Dept Biol Chem, Athens 11527, Greece

Paudel, Yam Nath
论文数: 0 引用数: 0
h-index: 0
机构:
Monash Univ Malaysia, Jeffrey Cheah Sch Med & Hlth Sci, Neuropharmacol Res Lab, Bandar Sunway 47500, Selangor, Malaysia Natl & Kapodistrian Univ Athens, Med Sch, Dept Biol Chem, Athens 11527, Greece

Papageorgiou, Sokratis G.
论文数: 0 引用数: 0
h-index: 0
机构:
Natl & Kapodistrian Univ Athens, Med Sch, Dept Biol Chem, Athens 11527, Greece Natl & Kapodistrian Univ Athens, Med Sch, Dept Biol Chem, Athens 11527, Greece

Piperi, Christina
论文数: 0 引用数: 0
h-index: 0
机构:
Natl & Kapodistrian Univ Athens, Med Sch, Dept Biol Chem, Athens 11527, Greece Natl & Kapodistrian Univ Athens, Med Sch, Dept Biol Chem, Athens 11527, Greece
[6]
2021 Alzheimer's disease facts and figures
[J].
不详
.
ALZHEIMERS & DEMENTIA,
2021, 17 (03)
:327-406

不详
论文数: 0 引用数: 0
h-index: 0
[7]
Socioeconomic Position and Late-Onset Dementia: A Nationwide Register-Based Study
[J].
Appel, Andreas M.
;
Bronnum-Hansen, Henrik
;
Garde, Anne H.
;
Hansen, Ase Marie
;
Ishtiak-Ahmed, Kazi
;
Islamoska, Sabrina
;
Mortensen, Erik L.
;
Nabe-Nielsen, Kirsten
.
JOURNAL OF AGING AND HEALTH,
2022, 34 (02)
:184-195

Appel, Andreas M.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark
Rigshosp, Danish Dementia Res Ctr, Copenhagen, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark

Bronnum-Hansen, Henrik
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark

Garde, Anne H.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark
Natl Res Ctr Working Environm, Copenhagen, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark

Hansen, Ase Marie
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark
Natl Res Ctr Working Environm, Copenhagen, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark

Ishtiak-Ahmed, Kazi
论文数: 0 引用数: 0
h-index: 0
机构:
Aarhus Univ Hosp Psychiat, Dept Depress & Anxiety, Aarhus, Denmark
Aarhus Univ, Dept Clin Med, Aarhus, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark

Islamoska, Sabrina
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark

Mortensen, Erik L.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark

Nabe-Nielsen, Kirsten
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark Univ Copenhagen, Dept Publ Hlth, Oster Farimagsgade 5,Postboks 2099, DK-1017 Copenhagen, Denmark
[8]
Exposure to As-, Cd-, and Pb-Mixture Induces Aβ, Amyloidogenic APP Processing and Cognitive Impairments via Oxidative Stress-Dependent Neuroinflammation in Young Rats
[J].
Ashok, Anushruti
;
Rai, Nagendra Kumar
;
Tripathi, Sachin
;
Bandyopadhyay, Sanghamitra
.
TOXICOLOGICAL SCIENCES,
2015, 143 (01)
:64-80

Ashok, Anushruti
论文数: 0 引用数: 0
h-index: 0
机构:
Acad Sci & Innovat Res, Lucknow, Uttar Pradesh, India
Div Dev Toxicol, Lucknow 226001, Uttar Pradesh, India Acad Sci & Innovat Res, Lucknow, Uttar Pradesh, India

Rai, Nagendra Kumar
论文数: 0 引用数: 0
h-index: 0
机构:
Acad Sci & Innovat Res, Lucknow, Uttar Pradesh, India
Div Dev Toxicol, Lucknow 226001, Uttar Pradesh, India Acad Sci & Innovat Res, Lucknow, Uttar Pradesh, India

Tripathi, Sachin
论文数: 0 引用数: 0
h-index: 0
机构:
Div Dev Toxicol, Lucknow 226001, Uttar Pradesh, India Acad Sci & Innovat Res, Lucknow, Uttar Pradesh, India

Bandyopadhyay, Sanghamitra
论文数: 0 引用数: 0
h-index: 0
机构:
Acad Sci & Innovat Res, Lucknow, Uttar Pradesh, India
Div Dev Toxicol, Lucknow 226001, Uttar Pradesh, India Acad Sci & Innovat Res, Lucknow, Uttar Pradesh, India
[9]
Epigenetic effects of natural polyphenols: A focus on SIRT1-mediated mechanisms
[J].
Ayissi, Vincent B. Owona
;
Ebrahimi, Azadeh
;
Schluesenner, Hermann
.
MOLECULAR NUTRITION & FOOD RESEARCH,
2014, 58 (01)
:22-32

Ayissi, Vincent B. Owona
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Tubingen, Inst Pathol, Dept Neuropathol, Div Immunopathol Nervous Syst, Tubingen, Germany
Univ Yaound I, Lab Pharmacol & Toxicol, Yaounde, Cameroon Univ Tubingen, Inst Pathol, Dept Neuropathol, Div Immunopathol Nervous Syst, Tubingen, Germany

Ebrahimi, Azadeh
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Tubingen, Inst Pathol, Dept Neuropathol, Div Immunopathol Nervous Syst, Tubingen, Germany
Univ Tubingen, Grad Sch Cellular & Mol Neurosci, Tubingen, Germany Univ Tubingen, Inst Pathol, Dept Neuropathol, Div Immunopathol Nervous Syst, Tubingen, Germany

Schluesenner, Hermann
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Tubingen, Inst Pathol, Dept Neuropathol, Div Immunopathol Nervous Syst, Tubingen, Germany Univ Tubingen, Inst Pathol, Dept Neuropathol, Div Immunopathol Nervous Syst, Tubingen, Germany
[10]
Early-Onset Alzheimer's Disease: What Is Missing in Research?
[J].
Ayodele, Temitope
;
Rogaeva, Ekaterina
;
Kurup, Jiji T.
;
Beecham, Gary
;
Reitz, Christiane
.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS,
2021, 21 (02)

Ayodele, Temitope
论文数: 0 引用数: 0
h-index: 0
机构:
Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA
Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY 10032 USA
Columbia Univ, Dept Neurol, New York, NY 10032 USA Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA

Rogaeva, Ekaterina
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Toronto, Tanz Ctr Res Neurodegenerat Dis, 60 Leonard Ave, Toronto, ON M5T 0S8, Canada Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA

论文数: 引用数:
h-index:
机构:

Beecham, Gary
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Miami, John P Hussman Inst Human Genom, Miami, FL USA Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA

Reitz, Christiane
论文数: 0 引用数: 0
h-index: 0
机构:
Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA
Columbia Univ, Gertrude H Sergievsky Ctr, New York, NY 10032 USA
Columbia Univ, Dept Neurol, New York, NY 10032 USA
Columbia Univ, Sergievsky Ctr, Taub Inst Res Aging Brain, Dept Epidemiol, 630 168th St, New York, NY 10032 USA Columbia Univ, Taub Inst Res Alzheimers Dis & Aging Brain, New York, NY 10032 USA