Senescence blurs the line between innate and adaptive immune cells

被引：2

作者：

Quinn, Kylie M. ^{[1
,2
]}

Linterman, Michelle A. ^{[3
]}

机构：

[1] RMIT Univ, Sch Hlth & Biomed Sci, West Campus,Bldg 223,Level 2,Room 15,Plenty Rd, Bundoora, Vic 3083, Australia

[2] Monash Univ, Dept Biochem, Biomed Discovery Inst, Clayton, Vic 3800, Australia

[3] Babraham Inst, Babraham Res Campus, Cambridge CB22 3AT, England

来源：

IMMUNOLOGY AND CELL BIOLOGY | 2020年 / 98卷 / 06期

基金：

英国生物技术与生命科学研究理事会;

关键词：

CD8 T cell; immunosenescence; leishmania; NK cell; NKG2D; sestrin; NATURAL-KILLER; EXPRESSION;

D O I：

10.1111/imcb.12341

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In Covre et al. and Pereira et al., the authors demonstrate the parallels between senescent NK cells and senescent CD8 T cells, and formalise the mechanism by which senescent CD8 T cells become more NK cell-like, through the action of sestrins.

引用

页码：431 / 433

页数：3

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