Aspergillus "fungus ball" of the bladder after hematopoietic transplantation in a pediatric patient:: Successful treatment with intravesical voriconazole and surgery

被引：8

作者：

Gonzalez-Vicent, M. ^{[1
]}

Lassaletta, A.

Lopez-Pino, M. A.

Romero-Tejada, J. C.

de la Fuente-Trabado, M.

Diaz, M. A.

机构：

[1] Hosp Nino Jesus, Stem Cell Transplant Unit, Pediat Hematol Oncol Sect, Madrid, Spain

来源：

PEDIATRIC TRANSPLANTATION | 2008年 / 12卷 / 02期

关键词：

Aspergillus; fungus ball; bladder; hematopoietic transplant; pediatric;

D O I：

10.1111/j.1399-3046.2007.00871.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Aspergillosis is an important cause of mortality in allogeneic HSCT. A "fungus ball" formation of Aspergillus in the bladder has seldom been reported. We report a child that underwent HSCT and developed possible disseminated aspergillosis with an intravesical "fungus ball," diagnosed by genitourinary MRI and PCR of the mass that was removed from the bladder. It is important to consider this complication in a patient with HC after HSCT. The treatment included a combination of systemic antifungal therapy along with intravesical voriconazole and surgical removal.

引用

页码：242 / 245

页数：4

共 16 条

[1] Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus [J].

Ascioglu, S ;

Rex, JH ;

de Pauw, B ;

Bennett, JE ;

Bille, J ;

Crokaert, F ;

Denning, DW ;

Donnelly, JP ;

Edwards, JE ;

Erjavec, Z ;

Fiere, D ;

Lortholary, O ;

Maertens, J ;

Meis, JF ;

Patterson, TF ;

Ritter, J ;

Selleslag, D ;

Shah, PM ;

Stevens, DA ;

Walsh, TJ .

CLINICAL INFECTIOUS DISEASES, 2002, 34 (01) :7-14

[2] Genitourinary complications of sickle cell disease [J].

Bruno, D ;

Wigfall, DR ;

Zimmerman, SA ;

Rosoff, PM ;

Wiener, JS .

JOURNAL OF UROLOGY, 2001, 166 (03) :803-811

[3] Incidence and natural history of proliferative sickle cell retinopathy - Observations from a cohort study [J].

Downes, SM ;

Hambleton, IR ;

Chuang, EL ;

Lois, N ;

Serjeant, GR ;

Bird, AC .

OPHTHALMOLOGY, 2005, 112 (11) :1869-1875

[4] Is it time to abandon the use of amphotericin B bladder irrigation? [J].

Drew, RH ;

Arthur, RR ;

Perfect, JR .

CLINICAL INFECTIOUS DISEASES, 2005, 40 (10) :1465-1470

[5] Risks and outcomes of invasive fungal infections in pediatric patients undergoing allogeneic hematopoietic cell transplantation [J].

Dvorak, CC ;

Steinbach, WJ ;

Brown, JMY ;

Agarwal, R .

BONE MARROW TRANSPLANTATION, 2005, 36 (07) :621-629

[6] Aspergillus 'fungus ball' within a cadaveric renal transplant graft [J].

Johnston, O ;

Little, DM ;

Hickey, D ;

Conlon, PJ .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2004, 19 (05) :1317-1318

[7] Obstructive anuria due to fungal bezoars in a renal graft recipient [J].

Kamel, G ;

Stephan, A ;

Barbari, A ;

Kilani, H ;

Karam, A ;

Zeineh, S ;

Salmeh, P ;

Husni, R ;

Mokhbat, J ;

Khoury, J .

TRANSPLANTATION PROCEEDINGS, 2003, 35 (07) :2692-2693

[8] Clinicopathological features and risk factors of clinically overt haemorrhagic cystitis complicating bone marrow transplantation [J].

Leung, AYH ;

Mak, R ;

Lie, AKW ;

Yuen, KY ;

Cheng, VCC ;

Liang, R ;

Kwong, YL .

BONE MARROW TRANSPLANTATION, 2002, 29 (06) :509-513

[9] Treatment of post-hematopoietic stem cell transplantation hemorrhagic cystitis with intravesicular sodium hyaluronate [J].

Miodosky, M. ;

Abdul-Hai, A. ;

Tsirigotis, P. ;

Or, R. ;

Bitan, M. ;

Resnick, I. B. ;

Gesundheit, B. ;

Zilberman, I. ;

Ioffe, L. ;

Leubovic, A. ;

Slavin, S. ;

Shapira, M. Y. .

BONE MARROW TRANSPLANTATION, 2006, 38 (07) :507-511

[10] Successful treatment of disseminated Scedosporium infection in 2 lung transplant recipients:: Review of the literature and recommendations for management [J].

Musk, Michael ;

Chambers, Daniel ;

Chin, Weng ;

Murray, Ronan ;

Gabbay, Eli .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2006, 25 (10) :1268-1272

← 1 2 →